Synonyms
Leiomyoma of the glans penis; Myofibroma of the glans penis
Definition
Myointimoma is a rare but very distinctive benign intravascular myofibroblast proliferation, derived from intimal cells of the vessels that constitute the corpus spongiosum of the penis.
Clinical Features
Incidence
Myointimoma is very rare, with only few cases reported so far, including a series of 10 cases (Fetsch et al. 2000), a series of 5 juvenile cases (McKenney et al. 2007), and 4 case reports (Robbins and Kohler 2005; Vardar et al. 2007; Turner et al. 2009; Monsálvez et al. 2009).
Moreover, it is possible that some old reports of penile intravascular leiomyoma, intravascular leiomyomatosis, leiomyoma, late stage intravascular fasciitis, and solitary cutaneous myofibroma are lesions that would now be called myointimoma (McKenney et al. 2007).
Age
Myointimoma can occur both in the pediatric (Fetsch et al. 2000; McKenney et al. 2007; Turner et al. 2009) and adult population (Fetsch et al. 2000; Robbins...
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References and Further Reading
Fetsch, J. F., Brinsko, R. W., Davis, C. J., Jr., Mostofi, F. K., & Sesterhenn, I. A. (2000). A distinctive myointimal proliferation (‘myointimoma’) involving the corpus spongiosum of the glans penis: A clinicopathologic and immunohistochemical analysis of 10 cases. The American Journal of Surgical Pathology, 24(11), 1524–1530.
McKenney, J. K., Collins, M. H., Carretero, A. P., Boyd, T. K., Redman, J. F., & Parham, D. M. (2007). Penile myointimoma in children and adolescents: A clinicopathologic study of 5 cases supporting a distinct entity. The American Journal of Surgical Pathology, 31(10), 1622–1626.
Monsálvez, V., RodrÃguez-Peralto, J. L., Fuertes, L., Garrido, C., & López-Gómez, S. (2009). Myointimoma: A rare tumor of the penis. Actas Dermosifiliográficas, 100(6), 511–512.
Robbins, J. B., & Kohler, S. (2005). Penile nodule in a 54-year-old man: A case of a myointimoma. Journal of the American Academy of Dermatology, 53(6), 1084–1086.
Turner, B. M., Reith, J. D., & Al-Quran, S. Z. (2009). Penile myointimoma. Journal of Cutaneous Pathology, 36(7), 817–819. https://doi.org/10.1111/j.1600-0560.2008.01138.x.
Vardar, E., Gunlusoy, B., Arslan, M., & Kececi, S. (2007). Myointimoma of the glans penis. Pathology International, 57(3), 158–161.
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Taverna, C., Franchi, A. (2020). Myointimoma. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4858
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4858
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