Uropathology

2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Myoid Gonadal Stromal Tumor of the Testis

  • Maurizio ColecchiaEmail author
  • Alessia Bertolotti
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4857
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Definition

Myoid gonadal stromal tumor (MGST) is an emerging entity described in the WHO classification edited in 2016 (Moch et al. 2016) as neoplasm with “spindle-shaped cells showing features of smooth muscle and gonadal stroma.”

Clinical Features

  • Incidence

    It is a rare tumor with less than ten cases published.

  • Age

    In the cases published, this tumor occur in young adults, but it was firstly described in a 4-year-old boy (Evans 1977).

  • Site

    It occurs in the testis.

  • Treatment

    Orchiectomy or nodulectomy (if diagnosed after intraoperatory examination).

  • Outcome

    The clinical follow-up provided for all the reported patients were negative for recurrence or metastatic disease.

Macroscopy

The tumors are circumscribed, nonencapsulated intratesticular nodules ranged from 1.2 to 3.5 cm. In the published cases, no macroscopical figure has been provided (Kao and Ulbright 2014).

Microscopy

The tumor cells are uniform, bland, spindle with oval to spindled nuclei, sometimes entrapping at the periphery...
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References and Further Reading

  1. Evans, H. L. (1977). Unusual gonadal stromal tumor of the testis. Case report with ultrastructural observations. Archives of Pathology & Laboratory Medicine, 101(6), 317–320.Google Scholar
  2. Kao, C. S., & Ulbright, T. M. (2014). Myoid gonadal stromal tumor: A clinicopathologic study of three cases of a distinctive testicular tumor. American Journal of Clinical Pathology, 142(5), 675–682.PubMedCrossRefGoogle Scholar
  3. Moch, H., Humphrey, P. A., Ulbright, T. M., & Reuter, V. E. (2016). WHO classification of tumours of the urinary system and male genital organs (4th ed.). Lyon: IARC.Google Scholar
  4. Zhang, M., Kao, C. S., Ulbright, T. M., & Epstein, J. I. (2013). Testicular fibrothecoma: A morphologic and immunohistochemical study of 16 cases. American Journal of Surgical Pathology, 37(8), 1208–1214.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Uropathology Unit, Department of PathologyFondazione IRCCS Istituto Nazionale dei Tumori di MilanoMilanItaly
  2. 2.Department of PathologyFondazione IRCCS Istituto Nazionale dei Tumori di MilanoMilanItaly