Myxofibrosarcoma, Genitourinary Tract
- 3 Downloads
Fibromyxosarcoma; Myxoid fibrosarcoma; Myxoid malignant fibrous histiocytoma
Myxofibrosarcoma (MFS) is a malignant fibroblastic neoplasm mainly involving the superficial soft tissues of elderly patients, with variably prominent myxoid stroma and cellular pleomorphism.
MFS is a relatively common sarcoma type.
It is the most common sarcoma of adult and elderly patients.
It shows a slight male predominance.
MFS typically arises in the lower limbs and limb girdles, followed by the upper extremities. It is usually a superficial tumor, involving the subcutis and the dermis, whereas subfascial sites are involved in approximately one third of the patients. True genitourinary MFS have been observed in the penis (Mentzel et al. 1996), whereas cases reported in the kidney, retroperitoneum, spermatic cord, and prostate most likely represent examples of dedifferentiated liposarcoma (Resorlu et al. 2018; Ozkan et al. 2006; Tearada et al. 2012...
References and Further Reading
- Tearada, H., Nagata, M., Mugiya, S., & Ozono, S. (2012). High-grade myxofibrosarcoma presenting at the spermatic cord after radiotherapy for prostate cancer. BMJ Case Report, 2012. pii:bcr0320126082.Google Scholar