Synonyms
This tumor was previously named “multilocular cystic renal cell carcinoma.”
Definition
Multicystic tumor with septa containing individual or groups of clear cells with ISUP/WHO 2016 low nucleolar grade (1–2).
Clinical Features
Incidence
This tumor accounts for less than 1% of all renal tumors, usually incidentally discovered.
Age
It occurs in middle-age adults.
Sex
There is no difference between male and female.
Site
There is no site predilection.
Treatment
Partial or radical nephrectomy is the surgical treatment of choice.
Outcome
To date there are no evidence of recurrence or metastasis.
Macroscopy
The tumor consists exclusively of variably sized cysts separated by thin septa and filled with clear, serous, or gelatinous fluid (Fig. 1). Solid, grossly discernible tumor mural nodules are incompatible with the diagnosis.
The typical gross appearance of multilocular cystic renal neoplasm of low malignant...
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Further Reading
Suzigan, S., López-Beltrán, A., Montironi, R., et al. (2006). Multilocular cystic renal cell carcinoma : A report of 45 cases of a kidney tumor of low malignant potential. American Journal of Clinical Pathology, 125(2), 217–222.
Tretiakova, M., Mehta, V., Kocherginsky, M., Minor, A., Shen, S.S., Sirintrapun, S.J., Yao, J.L., Alvarado-Cabrero, I., Antic, T., Eggener, S.E., Picken, M.M., & Paner, G.P. (2018) Predominantly cystic clear cell renal cell carcinoma and multilocular cystic renal neoplasm of low malignant potential form a low-grade spectrum. Virchows Archiv, 473, 85–93. [Epub ahead of print].
Williamson, S. R., Halat, S., Eble, J. N., Grignon, D. J., Lopez-Beltran, A., Montironi, R., Tan, P. H., Wang, M., Zhang, S., Maclennan, G. T., Baldridge, L. A., & Cheng, L. (2012). Multilocular cystic renal cell carcinoma: Similarities and differences in immunoprofile compared with clear cell renal cell carcinoma. The American Journal of Surgical Pathology, 36(10), 1425–1433.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this entry
Cite this entry
Caliò, A., Segala, D., Martignoni, G. (2020). Multilocular Cystic Renal Neoplasm of Low Malignant Potential. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4855
Download citation
DOI: https://doi.org/10.1007/978-3-030-41894-6_4855
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-41893-9
Online ISBN: 978-3-030-41894-6
eBook Packages: MedicineReference Module Medicine