- 4 Downloads
Intestinal metaplasia of the urothelial mucosa
Mucinous metaplasia of the bladder is the replacement of the normal transitional type of epithelial lining by intestinal type of epithelium.
Mucinous metaplasia is a common lesion correlated to mechanical and chronic irritations, such as found in neurogenic bladders, long-term catheterized patients, lithiasis, and bladder exstrophy (Rubenwolf et al. 2013; Gordetsky and Epstein 2015). These etiological factors are a common with cystitis glandularis.
It is more common in elderly patients but may occur in pediatric age.
It is a common finding in both sexes.
It is more common in the bladder; moreover, it may occur in renal pelvis and ureter.
It is not required.
It is a benign lesion. However, because of high frequency of coexistence of mucinous metaplasia and adenocarcinoma, it was thought mucinous metaplasia could be a precursor of primary bladder adenocarcinoma...