Synonyms
Secondary tumors
Definition
Metastatic tumors are malignant neoplasms that involve urologic organs secondarily.
Clinical Features
Incidence
The incidence varies in different organs. Bladder is the most frequent site of secondary involvement along the urinary tract and male genital organs. Metastatic tumors to the bladder are mainly gastric carcinoma, skin tumors, lung and breast carcinoma. Colonic, prostatic, rectal, and cervical carcinomas involve the bladder with direct spread. The secondary involvement of the other genitourinary organs (testis, penis, kidney, and prostate) represents a small numerical entity but a source of stimulating diagnosis for the pathologist. Kidney and testis are mainly involved via hematogenous spread; the most common primary tumors for renal metastases are lung or controlateral kidney carcinomas; while prostatic carcinoma or gastrointestinal tract tumors can metastasize to the testis. Uncommon secondary tumors involving prostate and penis (Giunchi...
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References and Further Reading
Bates, A. W., & Baithun, S. I. (2000). Secondary neoplasms of the bladder are histological mimics of nontransitional cell primary tumours: Clinicopathological and histological features of 282 cases. Histopathology, 36, 32–40.
Giunchi, F., Vasuri, F., Valerio, V., et al. (2017). Unusual asymptomatic presentation of bladder cancer metastatic to the penis. Pathology, Research and Practice, 213, 717–720.
Scatena, C., Comin, C. E., Lapini, A., & Raspollini, M. R. (2013). Renal metastasis from pulmonary adenocarcinoma – the pathologist’s approach to an uncommon finding: Case report and review of the literature. Applied Immunohistochemistry & Molecular Morphology, 21, 460–463.
Ulbright, T. M., & Young, R. H. (2008). Metastatic carcinoma to the testis: A clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features. The American Journal of Surgical Pathology, 32, 1683–1693.
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Raspollini, M.R., Lopez-Beltran, A. (2020). Metastatic Tumors. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4846
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4846
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