Metaplastic Condition of the Bladder
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Bladder metaplasia; Leukoplakia (this term is referred to as keratinizing squamous metaplasia); Metaplasia of the bladder
Changes of the urothelium in response to local injury. Squamous metaplasia is the most common metaplasia seen in the urothelium. It consists in two forms: non-keratinizing squamous metaplasia seen in the bladder trigone (vaginal metaplasia) and keratinizing squamous metaplasia.
Squamous metaplasia of the bladder is common.
It occurs mainly in adult age.
Non-keratinizing squamous metaplasia occurs more in premenopausal women; it is responsive to estrogen production; thus, it occurs in the cervix. It arises without evidence of previous injury. Female-to-male ratio is 8:1.
Keratinizing squamous metaplasia occurs mainly in the males.
Trigone is the most common site of non-keratinizing squamous metaplasia in the female patients. Keratinizing squamous metaplasia in the males occurs mainly in bladder diverticula,...