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The family of metanephric tumors comprises a spectrum of lesions that are derived from the metanephric blastema such as metanephric adenoma, the most frequent, metanephric adenofibroma and the metanephric stromal tumor.
Metanephric adenoma of the kidney is an uncommon neoplasm usually discovered incidentally.
Metanephric adenoma occurs during the fifth decade of life. However, it is the most common epithelial neoplasm found in the kidneys of children.
It occurs most frequently in women.
There is no site predilection.
Partial or radical nephrectomy is the treatment of choice.
It is a benign neoplasm.
Roughly 10% of patients with this neoplasm present with polycythemia due to increased erythropoietin production.
Metanephric adenoma is usually a single, solid, well-circumscribed nodule with light brown cut surfaces of glassy quality. It is sharply demarcated from adjacent parenchyma....
References and Further Reading
- Kinney, S. N., Eble, J. N., Hes, O., et al. (2015). Metanephric adenoma: the utility of immunohistochemical and cytogenetic analyses in differential diagnosis, including solid variant papillary renal cell carcinoma and epithelial-predominant nephroblastoma. Modern Pathology, 28, 1236–1248.PubMedCrossRefGoogle Scholar