2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Mesonephric Remnant of the Prostate

  • Alessia Cimadamore
  • Silvia Gasparrini
  • Rodolfo MontironiEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4842


Proliferation of benign acini arranged in lobules or infiltrating between muscle bundles and prostatic acini without a stromal desmoplastic response (Bostwick et al. 2003; Chen et al. 2011).

Clinical Features

  • Incidence

    Present in <1% of transurethral resections and are rarely identified in needle biopsies.

  • Age

    Patients ranged in age from 66 to 82 years (mean, 72 years).

  • Sex


  • Site


  • Treatment

    Not required.

  • Outcome

    Benign not associated with increased risk of cancer.


Histologically mesonephric remnants are identical to what is seen in the female genital tract, being composed of small glandular structures lined by a single layer of cuboidal cells, with scant amounts of eosinophilic or amphophilic cytoplasm, usually with dense eosinophilic colloid-like intraluminal secretory material (Fig. 1) (Bostwick et al. 2003). In some cases, they are forming glands with papillary infoldings or micropapillary tufts or ill-formed small glands intermixed with spindle...
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References and Further Reading

  1. Bostwick, D. G., Qian, J., Ma, J., & Muir, T. E. (2003). Mesonephric remnants of the prostate: Incidence and histologic spectrum. Modern Pathology, 16, 630–635.PubMedCrossRefGoogle Scholar
  2. Chen, Y. B., Fine, S. W., & Epstein, J. I. (2011). Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: Findings at radical prostatectomy. American Journal of Surgical Pathology, 35(7), 1054–1061.PubMedCrossRefGoogle Scholar
  3. Hameed, O., & Humphrey, P. A. (2005). Immunohistochemistry in diagnostic surgical pathology of the prostate. Seminars in Diagnostic Pathology, 22, 88–104.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Alessia Cimadamore
    • 1
  • Silvia Gasparrini
    • 1
  • Rodolfo Montironi
    • 1
    Email author
  1. 1.Institute of Pathological Anatomy and HistopathologyPolytechnic University of the Marche Region (Ancona), United Hospitals AnconaAnconaItaly