Synonyms
Genitoperineal raphe cyst; Mucoid cyst of the penile skin; Parameatal cyst
Definition
Median raphe cyst is a cyst arising along the midline of the ventral side of the male genital area. It is commonly thought to be secondary to anomalies in fusion between genito-urethral folds and urethral plate. It is mostly asymptomatic, but it can enlarge owing to infection or trauma, or during adolescence, thus interfering with urinary and sexual functions.
Clinical Features
Incidence
It is a rare lesion, with no reported studies about the exact incidence of occurrence.
Age
Median raphe cyst often arises in childhood but may become evident later during growth. This could explain the bimodal peak of incidence in age that has been observed (childhood and young adults).
Sex
Male.
Site
Median raphe cyst may potentially arise from any site on the ventral side of the genital area, including the parameatus, glans penis, penile shaft, scrotum, and perineum.
Treatment
The suggested treatment is...
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References and Further Reading
Dini, M., Baroni, G., & Maurizio, C. (2001). Median raphe cyst of the penis: A report of two cases with immunohistochemical investigation. American Journal of Dermatopathology, 23, 320–324.
Hung, S., Tai-Di, C., Hsiang-Te, S., & Hsiao-Wen, C. (2012). Male median raphe cysts: Serial retrospective analysis and histopathological classification. Diagnostic Pathology, 7, 121.
Nishida, H., Kashima, K., Daa, T., Yada, N., Arakane, M., Matsuda, K., Kato, A., Shimizu, F., & Yokoyama, S. (2012). Pigmented median raphe cyst of the penis. Journal of Cutaneous Pathology, 8, 808–810.
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Trambaiolo Antonelli, C., Portelli, F. (2020). Median Raphe Cyst. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4841
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4841
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