Uropathology

2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Leiomyoma

  • Cecilia Taverna
  • Alessandro FranchiEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4837
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Definition

Leiomyoma is a benign tumor with smooth muscle cell differentiation.

Clinical Features

  • Incidence

    Leiomyoma is rare in the genitourinary tract. In the bladder, it represents 0.5% of all tumors, although it is the most common benign mesenchymal neoplasm, with approximately 250 cases reported so far (He et al. 2018). In the paratesticular region, it is the second more frequent benign mesenchymal neoplasm. Few cases are reported in other genitourinary sites (Cheville and Folpe 2016; Cheville et al. 2016; Fletcher et al. 2016).

  • Age

    The lesion can occur over a wide age range, especially in the bladder (21–80 years), while in the prostate, it is seen mostly in older patients (Cheville et al. 2016).

  • Sex

    The tumor has a female predominance in the bladder (Cheville and Folpe 2016).

  • Site

    The most common site of involvement is the bladder; other sites comprise renal pelvis, spermatic cord, epididymis, tunica albuginea, prostate, scrotum, and penis (Cheville and Folpe 2016; Cheville et...

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References and Further Reading

  1. Bremmer, F., Kessel, F. J., Behnes, C. L., Trojan, L., & Heinrich, E. (2012). Leiomyoma of the tunica albuginea, a case report of a rare tumour of the testis and review of the literature. Diagnostic Pathology, 7, 140.CrossRefGoogle Scholar
  2. Cheville, J., Folpe, A. (2016). Mesenchimal tumours; tumours of the urinary tract. In: Holger, M., Humphrey, P. A., Ulbright, T. M., & Reuter, V. E. (eds), WHO classification of tumours of the urinary system and male genital organs (4th ed.). Lyon: IARC.Google Scholar
  3. Cheville, J., Algaba, F., Epstein, J. I., Lopez-Beltran, A. (2016). Mesenchymal tumours; tumours of the prostate. In: Holger, M., Humphrey, P. A., Ulbright, T. M., & Reuter, V. E. (eds), WHO classification of tumours of the urinary system and male genital organs (4th ed.). Lyon: IARC.Google Scholar
  4. Fletcher, C. D. M., Folpe, A. L., Hornick, J. L. (2016). Mesenchymal tumours of the spermatic cord and testicular adnexa. In: Holger, M., Humphrey, P. A., Ulbright, T. M., & Reuter, V. E. (eds), WHO classification of tumours of the urinary system and male genital organs (4th ed.). Lyon: IARC.Google Scholar
  5. He, L., Li, S., Zheng, C., & Wang, C. (2018). Rare symptomatic bladder leiomyoma: Case report and literature review. The Journal of International Medical Research, 46(4), 1678–1684.CrossRefGoogle Scholar
  6. Salvarci, A., & Altinay, S. (2014). Leiomyoma of the prostate, a rare mesenchymal tumour. The West Indian Medical Journal, 63(1), 116–117.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Health SciencesUniversity of FlorenceFlorenceItaly
  2. 2.Department of Translational Research and of New Technologies in Medicine and SurgeryUniversity of PisaPisaItaly