2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran

Hematopoietic Neoplasms

  • Maria Rosaria RaspolliniEmail author
  • Antonio Lopez-Beltran
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4824


Hematolymphoid tumors; Lymphoid neoplasms; Lymphoid tumors


Malignant tumors of lymphoid origin involving the urinary tract or male genital organs as a primary or secondary disease

Clinical Features

  • Incidence

    Lymphomas and plasmacytomas of the urinary tract and male genital organs are uncommon findings comprising less than 1% of the tumors affecting these organs. In the majority of the cases, they are usually a part of metastatic spread of systemic disease. They represent less than 5% of all primary extranodal lymphomas; few case series and isolated case reports have been described (Schniederjan and Osunkoya 2009). In the testis, lymphoma represents the most common neoplasia in the men older than 50 years, it can also occur in young patients, and its incidence is increased in HIV-positive patients (Buzelin et al. 1994). Concerning plasmacytomas, few cases of pure testicular forms have been reported in literature, all cases affecting old patients (Ferry et al. 1997)....

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References and Further Reading

  1. Al-Abbadi, A. M., Hattab, E., Tarawneh, M., et al. (2007). Primary testicular and paratesticular lymphoma: A retrospective clinicopathologic study of 34 cases with emphasis on differential diagnosis. Archives of Pathology & Laboratory Medicine, 131, 1040–1046.Google Scholar
  2. Buzelin, F., Karam, G., Moreau, A., et al. (1994). Testicular tumor and the acquired immunodeficiency syndrome. European Urology, 26, 71–76.CrossRefGoogle Scholar
  3. Darby, S., & Hancock, B. W. (2005). Localised non-Hodgkin lymphoma of the testis: The sheffield lymphoma Gropu experience. International Journal of Oncology, 26, 1093–1099.PubMedGoogle Scholar
  4. Ferry, J., Young, R. H., & Scully, R. (1997). Testicular and epididymal plasmacytoma: A report of 7 cases, including three that were initial manifestation of plasma cell myeloma. The American Journal of Surgical Pathology, 21, 590–598.CrossRefGoogle Scholar
  5. Henley, J. D., Young, R. H., Wade, C. L., & Ulbright, T. M. (2004). Seminomas with exclusive intertubular growth. A report of 12 clinically and grossly inconspicuous tumors. The American Journal of Surgical Pathology, 28, 1163–1168.CrossRefGoogle Scholar
  6. Kempton, C. L., Kurtin, P. J., Inwards, D., et al. (1997). Malignant lymphoma of the bladder: Evidence from 36 cases that low-grade lymphoma of the MALT-type is the most common primary bladder lymphoma. The American Journal of Surgical Pathology, 21, 1324–1333.CrossRefGoogle Scholar
  7. Schniederjan, S. D., & Osunkoya, A. O. (2009). Lymphoid neoplasms of the urinary tract and male genital organs: A clinicopathological study of 40 cases. Modern Pathology, 22, 1057–1065.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Maria Rosaria Raspollini
    • 1
    Email author
  • Antonio Lopez-Beltran
    • 2
    • 3
  1. 1.Histopathology and Molecular DiagnosticsUniversity Hospital CareggiFlorenceItaly
  2. 2.Pathology Service, Champalimaud Clinical CenterLisbonPortugal
  3. 3.Unit of Anatomic Pathology, Department of SurgeryCordoba University Medical SchoolCordobaSpain