2020 Edition
| Editors: Maria Rosaria Raspollini, Antonio Lopez-Beltran


  • Alessandro FranchiEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-030-41894-6_4822


Hemangioma is a benign vascular tumor.

Clinical Features

  • Incidence

    Hemangioma of the urogenital tract is rare and reports consist mainly of single cases or small series. However, hemangiomas were detected in 8.8% of kidneys removed for end-stage renal disease.

  • Age

    It occurs at all ages, including infants. The median is in the sixth decade.

  • Sex

    Hemangiomas of the kidney and the bladder occur more frequently in males.

  • Site

    Urogenital hemangiomas arise more frequently in the kidney and the bladder.

  • Treatment

    Surgery is the primary treatment. Embolization of the lesion may be considered to reduce the bleeding.

  • Outcome

    Hemangioma is a benign tumor that does not recur after complete excision.


Grossly, hemangiomas appear as hemorrhagic lesions ranging in size from 0.5 to 9 cm.


Histologically, hemangiomasconsist of a well-demarcated but unencapsulated proliferation of variably sized blood vessels, lined by flattened endothelial cells with very scant...
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References and Further Reading

  1. Bean, G. R., Joseph, N. M., Gill, R. M., Folpe, A. L., Horvai, A. E., & Umetsu, S. E. (2017). Recurrent GNAQ mutations in anastomosing hemangiomas. Modern Pathology, 30, 722–727.CrossRefGoogle Scholar
  2. Brown, J. G., Folpe, A. L., Rao, P., Lazar, A. J., Paner, G. P., Gupta, R., Parakh, R., Cheville, J. C., & Amin, M. B. (2010). Primary vascular tumors and tumor-like lesions of the kidney: A clinicopathologic analysis of 25 cases. The American Journal of Surgical Pathology, 34, 942–949.CrossRefGoogle Scholar
  3. Büttner, M., Kufer, V., Brunner, K., Hartmann, A., Amann, K., & Agaimy, A. (2013). Benign mesenchymal tumours and tumour-like lesions in end-stage renal disease. Histopathology, 62, 229–236.CrossRefGoogle Scholar
  4. Cheng, L., Nascimento, A. G., Neumann, R. M., et al. (1999). Hemangioma of the urinary bladder. Cancer, 86, 498–504.CrossRefGoogle Scholar
  5. Montgomery, E., & Epstein, J. I. (2009). Anastomosing hemangioma of the genitourinary tract: A lesion mimicking angiosarcoma. The American Journal of Surgical Pathology, 33, 1364–1369.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Translational Research and of New Technologies in Medicine and SurgeryUniversity of PisaPisaItaly