Endocervicosis

Synonyms

Mucinous analogue of endometriosis; Müllerian tumor-like glandular lesion

Definition

Lesion with endocervical-type mucinous epithelium involving the wall of the urinary bladder.

Clinical Features

• Incidence

  Uncommon.

• Age

  Reproductive age.

• Sex

  Female.

• Site

  Bladder posterior wall or posterior dome.

• Treatment

  Partial cystectomy may be required.

Macroscopy

2–5 cm mass of the bladder wall.

Microscopy

Benign appearing or slightly atypical endocervical-type mucinous glands irregularly disposed in an extensively involved bladder wall. Some endocervical-type glands are cystically dilated. Peri-glandular fibrosis and edema may be present in some cases, and extravasated mucin may be in association with ruptured glands. The glands in endocervicosis are typically lined by cuboidal or flattened cells with eosinophilic cytoplasm (Fig. 1). One case showed extravesical pelvic soft tissue involvement (Young and Clement 1992).

Endocervicosis, Fig. 1

Endocervicosis: endocervical-type epithelium