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Bioactive Compounds of Chestnut (Castanea sativa Mill.)

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Bioactive Compounds in Underutilized Fruits and Nuts

Part of the book series: Reference Series in Phytochemistry ((RSP))

Abstract

Castanea genus includes several chestnut-producing species with ecological and economical interest. The current industrial processing of chestnut generates great amounts of by-products mostly epicarps and integuments; likewise, there is an immense volume of chestnut flowers, burs, and chestnut leaves that remain in the soil, often contributing to the development of insect larvae, which require effective management strategies. Both materials could be included in extraction processes aimed at recovering high-value bioactive compounds. Herein, the compounds with highest interest, as well as their main bioactivities, are thoroughly characterized in each chestnut component, viz., integuments, pericarps, flowers, bur, leaves, and chestnut tree bark.

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References

  1. Manos PS, Zhou Z-K, Cannon CH (2001) Systematics of Fagaceae: phylogenetic tests of reproductive trait evolution. Int J Plant Sci 162:1361–1379

    Article  Google Scholar 

  2. Bounous G (2005) The chestnut: a multipurpose resource for the new millennium. Acta Hortic 693:33–138

    Article  Google Scholar 

  3. Cruz BR, Abraão AS, Lemos AM, Nunes FM (2013) Chemical composition and functional properties of native chestnut starch (Castanea sativa Mill.). Carbohydr Polym 94:594–602

    Article  CAS  PubMed  Google Scholar 

  4. Barreira JCM, Casal S, Ferreira ICFR, Peres AM, Pereira JA, Oliveira MBPP (2012) Chemical characterization of chestnut cultivars from three consecutive years: chemometrics and contribution for authentication. Food Chem Toxicol 50:2311–2317

    Article  CAS  PubMed  Google Scholar 

  5. Borges O, Gonçalves B, Carvalho JLS, Correia PR, Silva AP (2008) Nutritional quality of chestnut (Castanea sativa Mill.) cultivars from Portugal. Food Chem 106:976–984

    Article  CAS  Google Scholar 

  6. Barreira JCM, Pereira JA, Oliveira MBPP, Ferreira ICFR (2010) Sugars profiles of different chestnut (Castanea sativa Mill.) and almond (Prunus dulcis) cultivars by HPLC-RI. Plant Food Hum Nutr 65:38–43

    Article  CAS  Google Scholar 

  7. Bernárdez MM, Miguélez JM, Queijeiro JG (2004) HPLC determination of sugars in varieties of chestnut fruits from Galicia (Spain). J Food Comp Anal 17:63–67

    Article  CAS  Google Scholar 

  8. Barreira JCM, Casal S, Ferreira ICFR, Oliveira MBPP, Pereira JA (2009a) Nutritional, fatty acid and triacylglycerol profiles of Castanea sativa Mill cultivars: a compositional and chemometric approach. J Agric Food Chem 57:2836–2842

    Article  CAS  PubMed  Google Scholar 

  9. Borges O, Carvalho JLS, Correia PR, Silva AP (2007) Lipid and fatty acid profiles of Castanea sativa Mill. Chestnuts of 17 native Portuguese cultivars. J Food Comp Anal 20:80–89

    Article  CAS  Google Scholar 

  10. Fernandes Â, Barreira JCM, António AL, Bento A, Botelho ML, Ferreira ICFR (2011) Assessing the effects of gamma irradiation and storage time in energetic value and in major individual nutrients of chestnuts. Food Chem Toxicol 49:2429–2432

    Article  CAS  PubMed  Google Scholar 

  11. Barreira JCM, Alves RC, Casal S, Ferreira ICFR, Oliveira MBPP, Pereira JA (2009b) Vitamin E profile as a reliable authenticity discrimination factor between chestnut (Castanea sativa Mill.) cultivars. J Agric Food Chem 57:5524–5528

    Article  CAS  PubMed  Google Scholar 

  12. Carocho M, Barros L, Antonio AL, Barreira JCM, Bento A, Kaluska I, Ferreira ICFR (2013) Analysis of organic acids in electron beam irradiated chestnuts (Castanea sativa Mill.): effects of radiation dose and storage time. Food Chem Toxicol 55:348–352

    Article  CAS  PubMed  Google Scholar 

  13. Gonçalves B, Borges O, Costa HC, Bennett R, Santos M, Silva AP (2010) Metabolite composition of chestnut (Castanea sativa Mill.) upon cooking: proximate analysis, fibre, organic acids and phenolics. Food Chem 122:154–160

    Article  CAS  Google Scholar 

  14. Ribeiro B, Rangel J, Valentão P, Andrade PB, Pereira JÁ, Bölke H, Seabra RM (2007) Organic acids in two Portuguese chestnut (Castanea sativa Miller) varieties. Food Chem 100:504–508

    Article  CAS  Google Scholar 

  15. Vasconcelos MCBM, Bennett RN, Rosa E, Ferreira-Cardoso JV (2007) Primary and secondary metabolite composition of kernels from three cultivars of Portuguese chestnut (Castanea sativa Mill.) at different stages of industrial transformation. J Agric Food Chem 55:3508–3516

    Article  CAS  Google Scholar 

  16. Pereira-Lorenzo S, Ramos-Cabrer AM, Díaz-Hernández MB, Ciordia-Ara M, Rios-Mesa D (2005) Chemical composition of chestnut cultivars from Spain. Sci Hortic 107:306–314

    Article  CAS  Google Scholar 

  17. Diehl JF (2002) Nuts shown to offer health benefits. Int News Fats Oils Rel Mat 13:134–138

    Google Scholar 

  18. Demiate IM, Oetterer M, Wosiacki G (2001) Characterization of chestnut (Castanea sativa Mill) starch for industrial utilization. Braz Arch Biol Technol 44:69–78

    Article  CAS  Google Scholar 

  19. Pazianas M, Butcher GP, Subhani JM, Finch PJ, Ang L, Collins C, Heaney RP, Zaidi M, Maxwell JD (2005) Calcium absorption and bone mineral density in celiacs after long term treatment with gluten-free diet and adequate calcium intake. Osteoporos Int 16:56–63

    Article  CAS  PubMed  Google Scholar 

  20. Sabaté J, Radak T, JJr B (2000) The role of nuts in cardiovascular disease prevention. In: Wildman R (ed) Handbook of nutraceuticals and functional foods. CRC Press, London, pp 261–267

    Google Scholar 

  21. Uttara B, Singh AV, Zamboni P, Mahajan RT (2009) Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 7:65–74

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  22. Barreira JCM, Ferreira ICFR, Oliveira MBPP, Pereira JA (2008) Antioxidant activities of the extracts from chestnut flower, leaf, skins and fruit. Food Chem 107:1106–1113

    Article  CAS  Google Scholar 

  23. Dinis L-T, Oliveira MM, Almeida J, Costa R, Gomes-Laranjo J, Peixoto F (2012) Antioxidant activities of chestnut nut of Castanea sativa Mill. (cultivar ‘Judia’) as function of origin ecosystem. Food Chem 132:1–8

    Article  CAS  PubMed  Google Scholar 

  24. Otles S, Selek I (2012) Phenolic compounds and antioxidant activities of chestnut (Castanea sativa Mill.) fruits. Qual Assur Saf Crop 4:199–205

    Article  CAS  Google Scholar 

  25. Neri L, Dimitri G, Sacchetti G (2010) Chemical composition and antioxidant activity of cured chestnuts from three sweet chestnut (Castanea sativa Mill.) ecotypesfromItaly. J Food Compos Anal 23:23–29

    Article  CAS  Google Scholar 

  26. Sapkota K, Park S-E, Kim J-E, Kim S, Choi H-K, Chun H-S, Kim S-J (2010) Antioxidant and antimelanogenic properties of chestnut flower extract. Biosci Biotechnol Biochem 74:1527–1533

    Article  CAS  PubMed  Google Scholar 

  27. Vasconcelos MCBM, Bennett RN, Quideau S, Jacquet R, Rosa EAS, Ferreira-Cardoso JV (2010) Evaluating the potential of chestnut (Castanea sativa Mill.) fruit pericarp and integument as a source of tocopherols, pigments and polyphenols. Ind Crop Prod 31:301–311

    Article  CAS  Google Scholar 

  28. Vázquez G, Fernández-Agulló A, Freire MS, Antorrena G, González-Álvarez J (2010) Chestnut bur extracts as antioxidants: optimization of the extraction stage. WIT Trans Ecol Environ 140:155–165

    Article  CAS  Google Scholar 

  29. Vázquez G, Fernández-Agulló A, Gómez-Castro C, Freire MS, Antorrena G, González-Álvarez J (2012) Response surface optimization of antioxidants extraction from chestnut (Castanea sativa) bur. Ind Crop Prod 35:126–134

    Article  CAS  Google Scholar 

  30. Vázquez G, Fontenla E, Santos J, Freire MS, González-Álvarez J, Antorrena G (2008) Antioxidant activity and phenolic content of chestnut (Castanea sativa) shell and eucalyptus (Eucalyptusglobulus) bark extracts. Ind Crop Prod 28:279–285

    Article  CAS  Google Scholar 

  31. Vázquez G, González-Álvarez J, Freire MS, Fernández-Agulló A, Santos J, Antorrena G (2009) Chestnut burs as a source of natural antioxidants. Chem Eng Trans 17:855–860

    Google Scholar 

  32. Vekiari SA, Gordon MH, García-Macías P, Labrinea H (2008) Extraction and determination of ellagic acid content in chestnut bark and fruit. Food Chem 110:1007–1011

    Article  CAS  PubMed  Google Scholar 

  33. Vaughan JG, Geissler CA (1997) The new Oxford book of food plants, 2nd edn. Oxford University Press, New York/Oxford

    Google Scholar 

  34. Ozcan T, Yilmaz-Ersan L, Akpinar-Bayizit A, Delikanli B (2017) Antioxidant properties of probiotic fermented milk supplemented with chestnut flour (Castanea sativa Mill.). J Food Process Preserv 41:e13156

    Article  CAS  Google Scholar 

  35. Silva BM, Andrade PB, Valentão P, Ferreres F, Seabra RM, Ferreira MA (2004) Quince (Cydonia oblonga miller) fruit (pulp, peel, and seed) and jam: antioxidant activity. J Agric Food Chem 52:4705–4712

    Article  CAS  PubMed  Google Scholar 

  36. Hu YY, Rawal A, Schmidt-Rohr K (2010) Strongly bound citrate stabilizes the apatite nanocrystals in bone. Proc Natl Acad Sci U S A 107:22425–22429

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  37. Baati T, Horcajada P, Gref R, Couvreur P, Serre C (2011) Quantification of fumaric acid in liver, spleen and urine by high-performance liquid chromatography coupled to photodiode-array detection. J Pharm Biomed Anal 56:758–762

    Article  CAS  PubMed  Google Scholar 

  38. Raybaudi-Massilia RM, Mosqueda-Melgar J, Martín-Belloso O (2009) Antimicrobial activity of malic acid against Listeria monocytogenes, Salmonella enteritidis and Escherichia coli O157:H7 in apple, pear and melon juices. Food Control 20:105–112

    Article  CAS  Google Scholar 

  39. Frati A, Landi D, Marinelli C, Gianni G, Fontana L, Migliorini M, Pierucci F, Garcia-Gil M, Meacci E (2014) Nutraceutical properties of chestnut flours: beneficial effects on skeletal muscle atrophy. Food Funct 5:2870–2883

    Article  CAS  PubMed  Google Scholar 

  40. Astorga MS, Rodríguez B, Díaz C, Rodríguez E (2011) Fatty acid profile in varieties of chestnut fruits from Tenerife (Spain). CyTA – J Food 9:7781

    Google Scholar 

  41. Morana A, Squillaci G, Paixão SM, Alves L, La Cara F, Moura P (2017) Development of an energy biorefinery model for chestnut (Castanea sativa Mill.) shells. Energies 10:1504–1518

    Article  CAS  Google Scholar 

  42. Squillaci G, Apone F, Sena LM, Carola A, Tito A, Bimonte M, De Lucia A, Colucci G, La Cara F, Morana A (2018) Chestnut (Castanea sativa Mill.) industrial wastes as a valued bioresource for the production of active ingredients. Process Biochem 64:228–236

    Article  CAS  Google Scholar 

  43. Moure A, Conde E, Falqué E, Domínguez H, Parajó JC (2014) Production of nutraceutics from chestnut burs by hydrolytic treatment. Food Res Int 65:359–366

    Article  CAS  Google Scholar 

  44. Vella FM, Laratta B, La Cara F, Morana A (2018) Recovery of bioactive molecules from chestnut (Castanea sativa Mill.) by-products through extraction by different solvents. Nat Prod Res 32:1022–1032

    Article  CAS  PubMed  Google Scholar 

  45. Pinto D, Braga N, Rodrigues F, Oliveira MBPP (2017a) Castanea sativa bur: an undervalued by-product but a promising cosmetic ingredient. Cosmetics 4:50–65

    Article  CAS  Google Scholar 

  46. Pinto D, Rodrigues F, Braga N, Santos J, Pimentel FB, Palmeira-de-Oliveira A, Oliveira MBPP (2017b) The Castanea sativa bur as a new potential ingredient for nutraceutical and cosmetic outcomes: preliminary studies. Food Funct 8:201–208

    Article  CAS  PubMed  Google Scholar 

  47. Conedera MC, Manetti MC, Giudici F, Amorini E (2004) Distribution and economic potential of the sweet chestnut (Castanea sativa Mill.) in Europe. Ecol Mediterr 30:179–193

    Google Scholar 

  48. Carocho M, Barros L, Bento A, Santos-Buelga C, Morales P, ICFR F (2014) Castanea sativa Mill. Flowers amongst the most powerful antioxidant matrices: a phytochemical approach in decoctions and infusions. Biomed Res Int 2014:232956

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  49. Barros L, Alves CT, Dueñas M, Silva S, Oliveira R, Carvalho AM, Henriques M, Santos-Buelga C, Ferreira ICFR (2013) Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties. Ind Crop Prod 44:104–110

    Article  CAS  Google Scholar 

  50. Barros L, Oliveira S, Carvalho AM, Ferreira ICFR (2010) In vitro antioxidant properties and characterization in nutrients and phytochemicals of six medicinal plants from the Portuguese folk medicine. Ind Crop Prod 32:572–579

    Article  CAS  Google Scholar 

  51. Barba FJ, Esteve MJ, Frígola A (2014) Bioactive components from leaf vegetable products. Stud Nat Prod Chem 41:321–346

    Article  CAS  Google Scholar 

  52. Tuyen PT, Xuan TD, Khang DT, Ahmad A, Quan NV, Tu Anh TT, Anh H, Minh TN (2017) Phenolic compositions and antioxidant properties in bark, flower, inner skin,kernel and leaf extracts of Castanea crenata Sieb. etZucc. Antioxidants (Basel) 6:31–46

    Article  CAS  Google Scholar 

  53. Živković J, Zeković Z, Mujić I, Gođevac D, Mojović M, Mujić A, Spasojević I (2009a) EPR spin-trapping and spin-probing spectroscopy in assessing antioxidant properties: example on extracts of catkin, leaves, and spiny burs of Castanea sativa. Food Biophys 4:126–133

    Article  Google Scholar 

  54. Munekata PES, Franco D, Trindade MA, Lorenzo JM (2016) Characterization of phenolic composition in chestnut leaves and beer residue by LC-DAD-ESI-MS. LWT – Food Sci Technol 68:52–58

    Article  CAS  Google Scholar 

  55. Reinoso BD, Couto D, Moure A, Fernandes E, Domínguez H, Parajó JC (2012) Optimization of antioxidants-extraction from Castanea sativa leaves. Chem Eng J 203:101–109

    Article  CAS  Google Scholar 

  56. Mujić A, Grdović N, Mujić I, Mihailović M, Živković J, Poznanović G, Vidaković M (2011) Antioxidative effects of phenolic extracts from chestnut leaves, catkins and spiny burs in streptozotocin-treated rat pancreatic β-cells. Food Chem 125:841–849

    Article  CAS  Google Scholar 

  57. Almeida IF, Costa PC, Bahia MF (2010) Evaluation of functional stability and batch-to-batch reproducibility of a Castanea sativa leaf extract with antioxidant activity. AAPS PharmSci Tech 11:120–125

    Article  CAS  Google Scholar 

  58. Almeida IF, Maleckova J, Saffi R, Monteiro H, Góios F, Amaral MH, Costa PC, Garrido J, Silva P, Pestana N, Bahia MF (2015a) Characterization of an antioxidant surfactant-free topical formulation containing Castanea sativa leaf extract. Drug Dev Ind Pharm 41:148–155

    Article  CAS  PubMed  Google Scholar 

  59. Almeida IF, Pinto AS, Monteiro C, Monteiro H, Belo L, Fernandes J, Bento AR, Duarte TL, Garrido J, Bahia MF, Lobo JMS, Costa PC (2015b) Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a human keratinocytecellline. J Photochem Photobiol B Biol 144:28–34

    Article  CAS  Google Scholar 

  60. Basile A, Sorbo S, Giordano S, Ricciardi L, Ferrara S, Montesano D, Castaldo CR, Vuoto ML, Ferrara L (2000) Antibacterial and allelopathic activity of extract from Castanea sativa leaves. Fitoterapia 71:110–116

    Article  Google Scholar 

  61. Comandini P, Lerma-García MJ, Simó-Alfonso EF, Toschi TG (2014) Tannin analysis of chestnut bark samples (Castanea sativa Mill.) by HPLC-DAD-MS. Food Chem 157:290–295

    Article  CAS  PubMed  Google Scholar 

  62. Lampire O, Mila I, Raminosoa M, Michon V, Du Penhoat CH, Faucheur N, Leprevote O, Scalbert A (1998) Polyphenols isolated from the bark of Castanea sativa Mill. Chemical structures and auto-association in honour of professor G. H. Neil Towers 75th birthday. Phytochemistry 49:623–631

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Bragança, Portugal

    João C. M. Barreira & Isabel C. F. R. Ferreira

  2. Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal

    M. Beatriz P. P. Oliveira

Authors
  1. João C. M. Barreira
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  2. Isabel C. F. R. Ferreira
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  3. M. Beatriz P. P. Oliveira
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Corresponding author

Correspondence to M. Beatriz P. P. Oliveira .

Editor information

Editors and Affiliations

  1. Department of Botany, Karnatak University, Dharwad, India

    Hosakatte Niranjana Murthy

  2. Department of Biotechnology, Shivaji University, Kolhapur, India

    Vishwas Anant Bapat

Section Editor information

  1. Department of Botany, Karnatak University, Dharwad, India

    Hosakatte Niranjana Murthy

  2. Department of Horticulture, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Chenogju, Republic of Korea

    Hosakatte Niranjana Murthy

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Barreira, J.C.M., Ferreira, I.C.F.R., Oliveira, M.B.P.P. (2020). Bioactive Compounds of Chestnut (Castanea sativa Mill.). In: Murthy, H., Bapat, V. (eds) Bioactive Compounds in Underutilized Fruits and Nuts. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-06120-3_18-1

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  • DOI: https://doi.org/10.1007/978-3-030-06120-3_18-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-06120-3

  • Online ISBN: 978-3-030-06120-3

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