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Table 4 Multivariate analysis (Cox model) or risk for local recurrence (at Any Time) among 740 patients in the Intergroup trial and Intergroup nonrandomized subgroup

From: Treatment of Primary Melanomas

Factor

Risk ratio

p value

Tumor ulceration

6.3

0.001

Anatomic site:

  

 Head/neck

9.4

0.01

 Extremity

3.5

0.14

 Trunk

2.5

0.24

Tumor thickness

 (<2.0 mm versus >2 mm)

2.0

0.14

Surgical margin

 (2 cm versus 4 cm)

1.0

0.79

Surgical wound closure

 (skin graft versus primary closure)

0.9

0.75