Infectious Disorders of the Central Nervous System and Epileptic Seizures
Cerebral infectious disorders are notable for their considerable long-term morbidity. The well-known sequelae of cerebral infections include motor disorders, cognitive and psycho-developmental deficits, and visual and auditory impairments. Only recently, however, epilepsy has been shown to be associated with a variety of cerebral infections across several geographic regions.
Overall Frequency/Prevalence/Incidence/Contribution to Epilepsy
Burden of Epilepsy
The World Health Organization estimates that there are 50 million people with epilepsy worldwide. Three-fourths of these people reside in resource-poor countries, representing a huge burden. However, it has also been shown that the incidence of epilepsies and unprovoked seizures in some of the resource-poor countries may be higher than incidence estimates for high-income countries (Jallon 2002).
Burden of Cerebral Infections
The global burden of cerebral infections is difficult to estimate mainly due to the large...
KeywordsHuman Immunodeficiency Virus Infection Bacterial Meningitis Temporal Lobe Epilepsy Invasive Aspergillosis Cerebral Malaria
We gratefully acknowledge the following people for providing us with the pathological illustrations: Prof. S. K. Shankar and Dr. A. Mahadevan, Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karanataka, India and Prof. Alfonso Escobar, Universidad Autonoma de Mexico, Mexico City, Mexico.