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Infectious Disorders of the Central Nervous System and Epileptic Seizures

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Atlas of Epilepsies
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Short Description

Cerebral infectious disorders are notable for their considerable long-term morbidity. The well-known sequelae of cerebral infections include motor disorders, cognitive and psycho-developmental deficits, and visual and auditory impairments. Only recently, however, epilepsy has been shown to be associated with a variety of cerebral infections across several geographic regions.

Overall Frequency/Prevalence/Incidence/Contribution to Epilepsy

Burden of Epilepsy

The World Health Organization estimates that there are 50 million people with epilepsy worldwide. Three-fourths of these people reside in resource-poor countries, representing a huge burden. However, it has also been shown that the incidence of epilepsies and unprovoked seizures in some of the resource-poor countries may be higher than incidence estimates for high-income countries (Jallon 2002).

Burden of Cerebral Infections

The global burden of cerebral infections is difficult to estimate mainly due to the large...

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References

  • Annegers JF, Hauser WA, Beghi E, Nicolosi A, Kurland LT (1988) The risk of unprovoked seizures after encephalitis and meningitis. Neurology 38:1407–1410

    CAS  PubMed  Google Scholar 

  • Annegers JF, Rocca WA, Hauser WA (1996) Causes of epilepsy: contributions of the Rochester epidemiology project. Mayo Clin Proc 71:570–575

    Article  CAS  PubMed  Google Scholar 

  • Bern C, Garcia HH, Evans C, Gonzalez AE, Verastegui M, Tsang VC et al. (1999) Magnitude of the disease burden from neurocysticercosis in a developing country. Clin Infect Dis 29:1203–1209

    Article  CAS  PubMed  Google Scholar 

  • Garcia HH, Del Brutto OH (1999) Heavy nonencephalitic cerebral cysticercosis in tapeworm carriers. The cysticercosis working group in Peru. Neurology 53:1582–1584

    CAS  PubMed  Google Scholar 

  • Jallon P (2002) Epilepsy and epileptic disorders, an epidemiological marker? Contribution of descriptive epidemiology. Epileptic Disord 4:1–13

    PubMed  Google Scholar 

  • Johnson RT (1996) Acute encephalitis. Clin Infect Dis 23:219–224; quiz 225–226

    CAS  PubMed  Google Scholar 

  • Marks DA, Kim J, Spencer DD, Spencer SS (1992) Characteristics of intractable seizures following meningitis and encephalitis. Neurology 42:1513–1518

    CAS  PubMed  Google Scholar 

  • Misra UK, Tan CT, Kalita J (2008) Viral encephalitis and epilepsy. Epilepsia 49(Suppl 6):13–18

    Article  PubMed  Google Scholar 

  • Murthy JM, Prabhakar S (2008) Bacterial meningitis and epilepsy. Epilepsia 49(Suppl 6):8–12

    Article  PubMed  Google Scholar 

  • Ngoungou EB, Preux PM (2008) Cerebral malaria and epilepsy. Epilepsia 49(Suppl 6):19–24

    Article  PubMed  Google Scholar 

  • Nicolosi A, Hauser WA, Musicco M, Kurland LT (1991) Incidence and prognosis of brain abscess in a defined population: Olmsted County, Minnesota, 1935–1981. Neuroepidemiology 10:122–131

    Article  CAS  PubMed  Google Scholar 

  • Pomeroy SL, Holmes SJ, Dodge PR, Feigin RD (1990) Seizures and other neurologic sequelae of bacterial meningitis in children. N Engl J Med 323:1651–1657

    Article  CAS  PubMed  Google Scholar 

  • Rajashekhar V (2003) Solitary cerebral cysticercus granuloma. Epilepsia 44(Suppl 1):25–28

    Article  PubMed  Google Scholar 

  • Satishchandra P, Sinha S (2008) Seizures in HIV-seropositive individuals: NIMHANS experience and review. Epilepsia 49(Suppl 6):33–41

    Article  PubMed  Google Scholar 

  • Singh G, Prabhakar S (2002) Taenia solium cysticercosis: from basic to clinical science. CABI Publishing, Oxfordshire

    Book  Google Scholar 

  • Singh G, Prabhakar S (2008) The association between central nervous system (CNS) infections and epilepsy: epidemiological approaches and microbiological and epileptological perspectives. Epilepsia 49(Suppl 6):2–7

    Article  PubMed  Google Scholar 

  • Singla M, Singh P, Kaushal S, Bansal R, Singh G (2007) Hippocampal sclerosis in association with neurocysticercosis. Epileptic Disord 9:292–299

    PubMed  Google Scholar 

  • Theodore WH, Epstein L, Gaillard WD, Shinnar S, Wainwright MS, Jacobson S (2008) Human herpes virus 6B: a possible role in epilepsy? Epilepsia 49:1828–1837

    Article  PubMed  Google Scholar 

  • Vezzani A, Granata T (2005) Brain inflammation in epilepsy: experimental and clinical evidence. Epilepsia 46:1724–1743

    Article  CAS  PubMed  Google Scholar 

  • Wadia N, Desai S, Bhatt M (1988) Disseminated cysticercosis. New observations, including CT scan findings and experience with treatment by praziquantel. Brain 111(Pt 3):597–614

    Article  PubMed  Google Scholar 

  • Wilson M, Bryan RT, Fried JA, Ware DA, Schantz PM, Pilcher JB et al. (1991) Clinical evaluation of the cysticercosis enzyme-linked immunoelectrotransfer blot in patients with neurocysticercosis. J Infect Dis 164:1007–1009

    CAS  PubMed  Google Scholar 

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Acknowledgment

We gratefully acknowledge the following people for providing us with the pathological illustrations: Prof. S. K. Shankar and Dr. A. Mahadevan, Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karanataka, India and Prof. Alfonso Escobar, Universidad Autonoma de Mexico, Mexico City, Mexico.

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Singh, G., Sinha, S. (2010). Infectious Disorders of the Central Nervous System and Epileptic Seizures. In: Panayiotopoulos, C.P. (eds) Atlas of Epilepsies. Springer, London. https://doi.org/10.1007/978-1-84882-128-6_19

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  • DOI: https://doi.org/10.1007/978-1-84882-128-6_19

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-127-9

  • Online ISBN: 978-1-84882-128-6

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