Infectious Disorders of the Central Nervous System and Epileptic Seizures

  • Gagandeep Singh
  • Sanjib Sinha
Reference work entry

Short Description

Cerebral infectious disorders are notable for their considerable long-term morbidity. The well-known sequelae of cerebral infections include motor disorders, cognitive and psycho-developmental deficits, and visual and auditory impairments. Only recently, however, epilepsy has been shown to be associated with a variety of cerebral infections across several geographic regions.

Overall Frequency/Prevalence/Incidence/Contribution to Epilepsy

Burden of Epilepsy

The World Health Organization estimates that there are 50 million people with epilepsy worldwide. Three-fourths of these people reside in resource-poor countries, representing a huge burden. However, it has also been shown that the incidence of epilepsies and unprovoked seizures in some of the resource-poor countries may be higher than incidence estimates for high-income countries (Jallon 2002).

Burden of Cerebral Infections

The global burden of cerebral infections is difficult to estimate mainly due to the large...


Human Immunodeficiency Virus Infection Bacterial Meningitis Temporal Lobe Epilepsy Invasive Aspergillosis Cerebral Malaria 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We gratefully acknowledge the following people for providing us with the pathological illustrations: Prof. S. K. Shankar and Dr. A. Mahadevan, Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karanataka, India and Prof. Alfonso Escobar, Universidad Autonoma de Mexico, Mexico City, Mexico.


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Copyright information

© Springer-Verlag London Limited 2010

Authors and Affiliations

  • Gagandeep Singh
    • 1
  • Sanjib Sinha
    • 2
  1. 1.Department of NeurologyDayanand Medical CollegeLudhianaIndia
  2. 2.Department of NeurologyNational Institute of Mental Health and NeurosciencesBangaloreIndia

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