Therapeutic Endoscopy in the Management of Pancreatic Cancer

  • Alyson McGhan
  • Rebecca Burbridge
Reference work entry


Endoscopic retrograde cholangiopancreatography (ERCP) is a safe and reliable method for the diagnosis, treatment, and palliation of pancreaticobiliary malignancy. In 2015, the estimated new cases of pancreatic cancer were about 48,960. The 5-year survival of pancreatic cancer is dismal at approximately 5% Siegel et al. (CA: Cancer J Clin 65(1):5–29, 2015). ERCP provides less invasive approaches to diagnosis with examination of the biliary and pancreatic ducts. The procedure also allows for therapeutic relief of biliary obstruction. Advanced endoscopic techniques offer palliation of symptoms related to advanced pancreatic cancer and improvement in quality of life. This chapter addresses the use of therapeutic endoscopy in the diagnosis and management of pancreatic adenocarcinoma.


ERCP FISH Cholangioscopy Intraductal stricture biopsy Self-expandable metal stent Fiducial Celiac plexus neurolysis 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of GastroenterologyDuke University Medical CenterDurhamUSA

Section editors and affiliations

  • James L. Abbruzzese
    • 1
  • Raul A. Urrutia
    • 2
  • John Neoptolemos
    • 3
  • Markus W. Büchler
    • 4
  1. 1.Duke University Medical CenterDurhamUSA
  2. 2.Mayo Clinic Cancer CenterMayo ClinicRochesterUSA
  3. 3.Division of Surgery and OncologyUniversity of LiverpoolLiverpoolUK
  4. 4.Department of General, Visceral and Transplantation SurgeryUniversity of HeidelbergHeidelbergGermany

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