Pancreatic Cancer pp 1021-1037 | Cite as

New Japanese Classification of Pancreatic Cancer

  • Shuji Isaji
  • Yasuhiro Murata
  • Masashi Kishiwada
Reference work entry


Background: The Japanese classification of pancreatic cancer, seventh edition, has been released by Japan Pancreas Society (JPS) in July 2016.

Methods: Revision concepts and major revision points of the seventh edition of Japanese classification of the pancreatic cancers were reviewed.

Results: The principal points of revision are as follows:
  1. 1.

    Definition of the parts of the pancreas.

  2. 2.

    T category and stage grouping: consistency with those of the UICC seventh edition was obtained.

  3. 3.

    Reappraisal of anatomy of extrapancreatic nerve plexuses.

  4. 4.

    N category: classification based on numbers of lymph nodal metastasis among the regional lymph nodes; N1a, metastasis in one to three regional lymph nodes; and N1b, metastasis in four or more regional lymph nodes.

  5. 5.

    Histopathological classification which is consistent with the WHO classification.


The following new items have been added: (1) diagnostic guideline of tumor extension and lymph node metastasis based on multidetector CT (MD-CT), (2) objective criteria defining resectability status only based on the findings of MD-CT, (3) cytopathology guideline, and (4) criteria of histological response to drug therapy and/or radiotherapy.

Conclusion: The revised seventh edition of JPS pancreatic cancer classification focuses on establishing consistency to UICC seventh edition, while originality of JPS classification is maintained.


Pancreatic cancer Japanese classification Staging system UICC/AJCC staging system 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Shuji Isaji
    • 1
  • Yasuhiro Murata
    • 1
  • Masashi Kishiwada
    • 1
  1. 1.Hepatobiliary Pancreatic and Transplant SurgeryMie University School of MedicineTsuJapan

Section editors and affiliations

  • James L. Abbruzzese
    • 1
  • Raul A. Urrutia
    • 2
  • John Neoptolemos
    • 3
  • Markus W. Büchler
    • 4
  1. 1.Duke University Medical CenterDurhamUSA
  2. 2.Mayo Clinic Cancer CenterMayo ClinicRochesterUSA
  3. 3.Division of Surgery and OncologyUniversity of LiverpoolLiverpoolUK
  4. 4.Department of General, Visceral and Transplantation SurgeryUniversity of HeidelbergHeidelbergGermany

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