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Atlas of Genetic Diagnosis and Counseling pp 139–150Cite as

Angelman Syndrome

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Abstract

In 1965, Angelman reported three children with a similar pattern of severe learning disability, seizures, ataxic jerky movements, easily provoked laughter, absent speech, and dysmorphic facial features. The syndrome, which bears his name, was originally called the “happy puppet” syndrome. The incidence is estimated to be 1 in 12,000 to 1 in 20,000 (Clayton-Smith and Pembrey 1992; Petersen et al. 1995; Steffenburg et al. 1996).

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Authors and Affiliations

  1. Medical Genetics, Shriners Hospitals for Children, Perinatal and Clinical Genetics, Department of Pediatrics, LSU Health Sciences Center, Shreveport, LA, USA

    Harold Chen

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Chen, H. (2017). Angelman Syndrome. In: Atlas of Genetic Diagnosis and Counseling. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2401-1_13

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  • DOI: https://doi.org/10.1007/978-1-4939-2401-1_13

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