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Chronic Respiratory Disease, COPD

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  • First Online:
Encyclopedia of Metagenomics

  • 82 Accesses

Synonyms

Airway microbiome in COPD; Microbiota in COPD

Definition

The types, distribution, and environmental interactions of microbial communities present in the lungs of individuals with chronic obstructive pulmonary disease (COPD).

Introduction

Definition of COPD

The purpose of this entry is to introduce and summarize current knowledge of the airway microbiome in chronic obstructive pulmonary disease (COPD), a smoking-related illness. COPD is a highly prevalent disorder characterized by airflow obstruction that is not completely reversible and which exhibits increasing morbidity and mortality (Han et al. 2012). Classically two forms of clinical presentation were defined for COPD: chronic bronchitis and emphysema. Chronic bronchitis is characterized by excessive mucus production that results in airflow obstruction in the proximal airways. Emphysema is characterized by destruction of distal airway spaces in the lung, where gas exchange takes place.

However, COPD is now recognized to be...

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References

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Author information

Authors and Affiliations

  1. Pulmonary and Critical Care Medicine, School of Medicine, University of California San Francisco, 505 Parnassus Ave, 0130, San Francisco, CA, 94143, USA

    Yvonne Huang

Authors
  1. Yvonne Huang
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Corresponding author

Correspondence to Yvonne Huang .

Editor information

Editors and Affiliations

  1. Genomic Medicine, J. Craig Venter Institute, La Jolla, CA, USA

    Sarah K. Highlander

  2. Universidad Miguel Hernandez, Campus San Juan, San Juan, Alicante, Spain

    Francisco Rodriguez-Valera

  3. The Institute for Genomic Biology Department of Animal Sciences & Pathobiology Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA

    Bryan A. White

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© 2015 Springer Science+Business Media New York

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Huang, Y. (2015). Chronic Respiratory Disease, COPD. In: Highlander, S.K., Rodriguez-Valera, F., White, B.A. (eds) Encyclopedia of Metagenomics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7475-4_698

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