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HIV-2 Neurological Manifestations

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Encyclopedia of AIDS

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Definition

Neurological manifestations of HIV-2 include neurocognitive dysfunction and peripheral neuropathy. They may include primary complications caused by the HIV-2 virus or secondary complications due to opportunistic illnesses or toxicity of therapy that develops during chronic HIV-2 infection.

Neurological Disease from Human Immunodeficiency Virus (HIV) Infection

One of the most underappreciated aspects of retroviral infection has been the serious neurological complications that commonly occur. In the case of HIV-1, it is known that shortly after infection, the virus enters the nervous system and can be recovered from it at almost any time during the ongoing years of infection. As immune dysfunction develops, there is increasing prevalence of both neurocognitive decline and peripheral neuropathy. Furthermore, opportunistic neurological conditions such as cryptococcal meningitis, toxoplasmic encephalitis, cytomegalovirus encephalitis, progressive multifocal leukoencephalopathy,...

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Authors and Affiliations

  1. Department of Medicine, Washington University in St. Louis, St Louis, MO, 63110, USA

    Youngjee Choi

  2. Departments of Medicine and Neurology, Washington University in St. Louis, St Louis, MO, 63110, USA

    David B. Clifford

Authors
  1. Youngjee Choi
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  2. David B. Clifford
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Correspondence to Youngjee Choi .

Editor information

Editors and Affiliations

  1. Dept. Cell & Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA

    Thomas J. Hope

  2. Office of Graduate and Postdoctoral Studies, University of Miami, Miller School of Medicine, Miami, Florida, USA

    Mario Stevenson

  3. University of California, San Diego Dept. Pathology, La Jolla, California, USA

    Douglas Richman

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Choi, Y., Clifford, D.B. (2013). HIV-2 Neurological Manifestations. In: Hope, T., Stevenson, M., Richman, D. (eds) Encyclopedia of AIDS. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9610-6_51-1

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  • DOI: https://doi.org/10.1007/978-1-4614-9610-6_51-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-9610-6

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