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Burkitt and Burkitt-Like Lymphoma

  • Living reference work entry
  • First Online:
Encyclopedia of AIDS

  • 208 Accesses

Definition

Burkitt lymphoma (BL) is a rare tumor of mature B lymphocytes. Clinically, it develops rapidly and runs an aggressive course. Tumor can develop in any body organ, but most often involves sites other than lymph nodes, especially in the abdomen, pharynx, or the jaw. BL is relatively more common in sub-Saharan Africa, where it is endemic. Patients with HIV infection are also at increased risk of BL, and in this setting it is called epidemic BL. Endemic and epidemic BL are both associated with Epstein-Barr virus, a common virus that infects 90 % of the global population. Although the tumor is highly aggressive, being the most rapidly growing cancer known and doubling every 24 h, it is also very responsive to modern chemotherapy. With currently available regimens, 90 % of patients can expect to be cured when properly treated.

Introduction

In 1982, reports of Kaposi sarcoma and Pneumocystis carinii infections in men who have sex with men (MSM)heralded the advent of the AIDS...

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Author information

Authors and Affiliations

  1. AIDS Malignancy Program, Office of HIV and AIDS Malignancy & Infections and Immunoepidemiology Branch, National Cancer Institute, Bethesda, MD, USA

    Kishor Bhatia

  2. Infections and Immunoepidemiology Branch, National Cancer Institute, Bethesda, MD, USA

    Sam Mbulaiteye

Authors
  1. Kishor Bhatia
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  2. Sam Mbulaiteye
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Corresponding author

Correspondence to Kishor Bhatia .

Editor information

Editors and Affiliations

  1. Dept. Cell & Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA

    Thomas J. Hope

  2. Office of Graduate and Postdoctoral Studies, University of Miami, Miller School of Medicine, Miami, Florida, USA

    Mario Stevenson

  3. University of California, San Diego Dept. Pathology, La Jolla, California, USA

    Douglas Richman

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Bhatia, K., Mbulaiteye, S. (2013). Burkitt and Burkitt-Like Lymphoma. In: Hope, T., Stevenson, M., Richman, D. (eds) Encyclopedia of AIDS. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9610-6_21-1

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  • DOI: https://doi.org/10.1007/978-1-4614-9610-6_21-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-9610-6

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