Skip to main content
SpringerLink
Log in

HIV Antigen Processing and Presentation

  • Living reference work entry
  • First Online:
Book cover Encyclopedia of AIDS

  • 275 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References

  • Barouch DH, Stephenson KE, Borducchi EN, Smith K, Stanley K, McNally AG, Liu J, Abbink P, Maxfield LF, Seaman MS, et al. Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys. Cell. 2013;155:531–9.

    Article  PubMed  CAS  Google Scholar 

  • Blum JS, Wearsch PA, Cresswell P. Pathways of antigen processing. Annu Rev Immunol. 2013;31:443–73.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, et al. A blueprint for HIV vaccine discovery. Cell Host Microbe. 2012;12:396–407.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Hansen SG, Sacha JB, Hughes CM, Ford JC, Burwitz BJ, Scholz I, Gilbride RM, Lewis MS, Gilliam AN, Ventura AB, et al. Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms. Science. 2013;340:1237874.

    Article  PubMed  Google Scholar 

  • Hickman HD, Luis AD, Bardet W, Buchli R, Battson CL, Shearer MH, Jackson KW, Kennedy RC, Hildebrand WH. Cutting edge: class I presentation of host peptides following HIV infection. J Immunol. 2003;171:22–6.

    Article  PubMed  CAS  Google Scholar 

  • Johnson JA, Barouch DH, Baden LR. Nonreplicating vectors in HIV vaccines. Curr Opin HIV AIDS. 2013;8:412–20.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lazaro E, Kadie C, Stamegna P, Zhang SC, Gourdain P, Lai NY, Zhang M, Martinez SM, Heckerman D, Le Gall S. Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape. J Clin Invest. 2011;121:2480–92.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Le Gall S, Stamegna P, Walker BD. Portable flanking sequences modulate CTL epitope processing. J Clin Invest. 2007;117:3563–75.

    Article  PubMed  PubMed Central  Google Scholar 

  • Llano A, Williams A, Olvera A, Silva-Arrieta S, Brander C. Best-characterized HIV-1 CTL epitopes: the 2013 update. In: Yusim K, Korber B, Brander C, Barouch DH, de Boer R, Haynes BF, Koup RA, Moore JP, Walker BD, Watkins DI, editors. HIV molecular immunology 2013. Los Alamos: Los Alamos National Laboratory, Theoretical Biology and Biophysics; 2013. p. 3–25.

    Google Scholar 

  • Parks CL, Picker LJ, King CR. Development of replication-competent viral vectors for HIV vaccine delivery. Curr Opin HIV AIDS. 2013;8:402–11.

    Article  PubMed  PubMed Central  Google Scholar 

  • Picker LJ, Hansen SG, Lifson JD. New paradigms for HIV/AIDS vaccine development. Annu Rev Med. 2012;63:95–111.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Tenzer S, Wee E, Burgevin A, Stewart-Jones G, Friis L, Lamberth K, Chang CH, Harndahl M, Weimershaus M, Gerstoft J, et al. Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance. Nat Immunol. 2009;10:636–46.

    Article  PubMed  CAS  Google Scholar 

  • Yewdell JW. Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses. Immunity. 2006;25:533–43.

    Article  PubMed  CAS  Google Scholar 

  • Yewdell JW. Plumbing the sources of endogenous MHC class I peptide ligands. Curr Opin Immunol. 2007;19:79–86.

    Article  PubMed  CAS  Google Scholar 

  • Zhang SC, Martin E, Shimada M, Godfrey SB, Fricke J, Locastro S, Lai NY, Liebesny P, Carlson JM, Brumme CJ, et al. Aminopeptidase substrate preference affects HIV epitope presentation and predicts immune escape patterns in HIV-infected individuals. J Immunol. 2012;188:5924–34.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ragon Institute of MGH, MIT and Harvard, Harvard Medical School, Cambridge, MA, USA

    Julie Boucau & Marijana Rucevic

  2. Ragon Institute of MGH, MIT and Harvard, Massachusetts General Hospital, Harvard Medical School, 400 Technology Square, 02139, Cambridge, MA, USA

    Sylvie Le Gall

Authors
  1. Julie Boucau
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marijana Rucevic
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sylvie Le Gall
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Julie Boucau .

Editor information

Editors and Affiliations

  1. Dept. Cell & Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA

    Thomas J. Hope

  2. Office of Graduate and Postdoctoral Studies, University of Miami, Miller School of Medicine, Miami, Florida, USA

    Mario Stevenson

  3. University of California, San Diego Dept. Pathology, La Jolla, California, USA

    Douglas Richman

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media New York

About this entry

Cite this entry

Boucau, J., Rucevic, M., Le Gall, S. (2014). HIV Antigen Processing and Presentation. In: Hope, T., Stevenson, M., Richman, D. (eds) Encyclopedia of AIDS. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9610-6_175-1

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-9610-6_175-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-9610-6

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation