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Safety of Immunotherapy

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Encyclopedia of Medical Immunology
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Synonyms

Allergen immunotherapy; Allergen-specific desensitization; Allergy immunotherapy; Allergy injections; Allergy shots; Hyposensitization; Immunotherapy

Background

Although the benefits of immunotherapy have been well demonstrated for the treatment of many allergic conditions such as allergic rhinitis, allergic asthma, and stinging insect allergy (Casale and Stokes 2011), the risks of adverse reactions must be considered when immunotherapy is used.

Local Reactions

Localized reactions at the site of immunotherapy injections are fairly common, with frequencies ranging from 26 % to 82 % patients and 0.7 % to 4 % of injections (Cox et al. 2011). These local reactions may involve local erythema, swelling, and itching. In one survey of 249 patients undergoing immunotherapy and who experienced local reactions, 84.7 % reported reactions smaller than the palm of the hand, and 81.9 % classified local reactions as not bothersome at all or only slightly bothersome. Ninety-six percent of...

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References

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Correspondence to Thanai Pongdee .

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© 2014 Springer-Verlag Berlin Heidelberg

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Pongdee, T. (2014). Safety of Immunotherapy. In: Mackay, I.R., Rose, N.R., Ledford, D.K., Lockey, R.F. (eds) Encyclopedia of Medical Immunology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9194-1_526

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  • DOI: https://doi.org/10.1007/978-1-4614-9194-1_526

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-9193-4

  • Online ISBN: 978-1-4614-9194-1

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