Synonyms
Allergic contact dermatitis; Allergic contact eczema; Periocular dermatitis; Periocular eczema; Periorbital dermatitis; Periorbital eczema
Nomenclature and Definition
Contact allergy of the eyelid represents an inflammatory skin disease due to an antigen-specific T-cell-mediated immune response. Referring to the classification of allergic reactions published by Coombs and Gell (Gell and Coombs 1963), contact allergy is classified as “delayed-type” T-cell-mediated hypersensitivity reaction. Immediate-type reactions of contact allergy have also been reported, but are rare.
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References
Cooper SM, Shaw S. Eyelid dermatitis: an evaluation of 232 patch test patients over 5 years. Contact Dermatitis. 2000;42:291–3.
Feser A, Mahler V. Periorbital dermatitis: causes, differential diagnoses and therapy. J Dtsch Dermatol Ges. 2010;8:159–66.
Feser A, Plaza T, Vogelgsang L, Mahler V. Periorbital dermatitis - a recalcitrant disease: causes and differential diagnoses. Br J Dermatol. 2008;159:858–63.
Gell PGH, Coombs RRA. The classification of allergic reactions underlying disease. In: Coombs RRA, Gell PGH, editors. Clinical aspects of immunology, Blackwell Science; London 1963.
Kimber I, Basketter DA, Gerberick GF, Dearman RJ. Allergic contact dermatitis. Int Immunopharmacol. 2002;2:201–11.
Martin SF, Esser PR, Weber FC, Jakob T, Freudenberg MA, Schmidt M, Goebeler M. Mechanisms of chemical-induced innate immunity in allergic contact dermatitis. Allergy. 2011;66:1152–63.
Niebuhr M, Kapp A, Werfel T, Heratizadeh A. Allergic contact dermatitis and atopy. Hautarzt. 2011;62:744–50.
Peiser M, Tralau T, Heidler J, Api AM, Arts JH, Basketter DA, English J, Diepgen TL, Fuhlbrigge RC, Gaspari AA, Johansen JD, Karlberg AT, Kimber I, Lepoittevin JP, Liebsch M, Maibach HI, Martin SF, Merk HF, Platzek T, Rustemeyer T, Schnuch A, Vandebriel RJ, White IR, Luch A. Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany. Cell Mol Life Sci. 2012;69:763–81.
Schnuch A, Aberer W, Agathos M, Becker D, Brasch J, Elsner P, Frosch PJ, Fuchs T, Geier J, Hillen U, Löffler H, Mahler V, Richter G, Szliska C, Deutsche Kontaktallergie-Gruppe. Performing patch testing with contact allergens. J Dtsch Dermatol Ges. 2008;6:770–5.
Schnuch A, Szliska C, Uter W, IVDK. Facial allergic contact dermatitis. Data from the IVDK and review of literature. Hautarzt. 2009;60:13–21.
Temesvári E, Pónyai G, Németh I, Hidvégi B, Sas A, Kárpáti S. Periocular dermatitis: a report of 401 patients. J Eur Acad Dermatol Venereol. 2009;23:124–8.
Uter W, Menezes de Pádua C, Pfahlberg A, Nink K, Schnuch A, Behrens-Baumann W. Contact allergy to topical ophthalmological drugs - epidemiological risk assessment. Klin Monbl Augenheilkd. 2009;226:48–53.
Werfel T, Kapp A. Atopic dermatitis and allergic contact dermatitis. In: Holgate ST, Church MK, Lichtenstein LM, editors. Allergy. Mosby; London 2006. p. 107–128.
Wittmann M, Werfel T. Interaction of keratinocytes with infiltrating lymphocytes in allergic eczematous skin diseases. Curr Opin Allergy Clin Immunol. 2006;6:329–34.
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Heratizadeh, A. (2014). Eyes and Eyelid, Contact Allergic Reaction On. In: Mackay, I.R., Rose, N.R., Ledford, D.K., Lockey, R.F. (eds) Encyclopedia of Medical Immunology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9194-1_464
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