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Hemozoin Biophysics and Drug Target

  • Living reference work entry
  • First Online:
Encyclopedia of Malaria

  • 423 Accesses

Synonyms

γ-resonance spectroscopy; Acylglycerols; Aqua- or hydroxoferriprotoporphyrin IX; Binding constant; Chloroferriprotoporphyrin IX; Electron spin resonance spectroscopy; Erythrocyte; Ferriprotoporphyrin IX; Ferroprotoporphyrin IX; Formation constant; Hematin anhydride; Infected red blood cells; Iron(II)protoporphyrin IX; Iron(III)protoporphyrin IX; Propanoate

Definitions

Cl-Fe(III)PPIX:

Hemin

Fe(II)PPIX:

Heme

Fe(III)PPIX:

Ferriheme

HO-Fe(III)PPIX or H2O-Fe(III)PPX:

Hematin

Reactive oxygen species:

Strong, reactive oxidants derived from O2, such as the hydroxyl radical (HO⋅), superoxide anion (O2 −), and hydrogen peroxide (H2O2)

Lath:

A thin, narrow strip

Coordination:

Bonding of a ligand to a metal ion via electron pair donation

Excitonic coupling:

Interaction between an electron and electron hole (site from which and electron has been excited) in a solid

Frenkel exciton:

A form of excitonic coupling in which the electron–hole pair (the exciton) is localized in a small part of...

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References

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Acknowledgment

Mr David Kuter is thanked for drawing the structures shown in Figs. 1, 2, and 4.

Author information

Authors and Affiliations

  1. Department of Chemistry, University of Cape Town, Private Bag, Rondebosch, 7701, Cape Town, South Africa

    Timothy J. Egan

Authors
  1. Timothy J. Egan
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Corresponding author

Correspondence to Timothy J. Egan .

Editor information

Editors and Affiliations

  1. Heswall, United Kingdom

    Marcel Hommel

  2. Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany

    Peter G. Kremsner

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Egan, T.J. (2013). Hemozoin Biophysics and Drug Target. In: Hommel, M., Kremsner, P. (eds) Encyclopedia of Malaria. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8757-9_6-1

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  • DOI: https://doi.org/10.1007/978-1-4614-8757-9_6-1

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  • Online ISBN: 978-1-4614-8757-9

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