Abbreviations
- ACBP:
-
Acyl-CoA-binding proteins
- ACP:
-
Acyl carrier protein
- ACS:
-
Acyl-CoA synthetase
- ADP:
-
Adenosine bisphosphate
- AGPAT:
-
1-Acyl-G3P acyltransferase
- ATP:
-
Adenosine triphosphate
- CCT, CTP:
-
Phosphocholine cytidylyltransferase
- CDP:
-
Cytidine bisphosphate
- CDP-Cho:
-
CDP-choline
- CDP-DAG:
-
CDP-diacylglycerol
- CDP-Etn:
-
CDP-ethanolamine
- CDS:
-
CDP-DAG synthase
- CEPT:
-
Choline/ethanolamine phosphotransferase
- CK:
-
Choline kinase
- CLS:
-
CL synthase
- CPT:
-
Cholinephosphotransferase
- CTP:
-
Cytidine triphosphate
- CL:
-
Cardiolipin
- CoA:
-
Coenzyme A
- DAG:
-
Diacylglycerol
- DHAP:
-
Dihydroxyacetone phosphate
- DHAPAT:
-
DHAP acyltransferase
- ECT, CTP:
-
Phosphoethanolamine cytidylyltransferase
- EK:
-
Ethanolamine kinase
- EPT:
-
Ethanolamine phosphotransferase
- FA:
-
Fatty acid
- FAE:
-
Fatty acid elongation
- FASII:
-
Type II fatty acid synthesis
- G3P:
-
Glycerol 3-phosphate
- G3PAT:
-
G3P acyltransferase
- GPI:
-
Glycosylphosphatidylinositol
- IRBC:
-
Infected red blood cells
- IP3 :
-
Inositol trisphosphate
- NPP:
-
New permeation pathways
- PA:
-
Phosphatidic acid
- PAP, PA:
-
Phosphatase
- PC:
-
Phosphatidylcholine
- PE:
-
Phosphatidylethanolamine
- PEMT:
-
PE N-methyltransferase
- PG:
-
Phosphatidylglycerol
- PGP:
-
Phosphatidylglycerophosphate
- PGPPase:
-
PGP phosphatase
- PGPS:
-
PGP synthase
- PPI:
-
Phosphoinositides
- PI:
-
Phosphatidylinositol
- PI(3)P:
-
Phosphatidylinositol-3-phosphate
- PI(3,4)P2:
-
Phosphatidylinositol-3,4-bisphosphate
- PI(3,5)P2 :
-
Phosphatidylinositol-3,5-bisphosphate
- PI(3,4,5)P3 or PIP3 :
-
Phosphatidylinositol-3,4,5-trisphosphate
- PI(4)P:
-
Phosphatidylinositol-4-phosphate
- PI(4,5)P2 or PIP2:
-
Phosphatidylinositol-4,5-bisphosphate
- PI-PLC:
-
Phosphoinositide-specific phospholipase C
- PIS:
-
PI synthase
- PL:
-
Phospholipid
- PLD:
-
Phospholipase D
- PLMT:
-
PL N-methyltransferase
- PMT:
-
Phosphoethanolamine N-methyltransferase
- PS:
-
Phosphatidylserine
- PSD:
-
PS decarboxylase
- PSS:
-
PS synthase
- PSSE:
-
PS synthase via base exchange
- RBC:
-
Red blood cells
- SCD:
-
Stearoyl-CoA desaturase
- SD:
-
Serine decarboxylase
- SDPM:
-
Serine decarboxylase-phosphoethanolamine methyltransferase
- SM:
-
Sphingomyelin
References
Aurrecoechea C, Brestelli J, Brunk BP, Dommer J, Fischer S, Gajria B, et al. PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res. 2009;37(Database issue):D539–43. Epub 2008/10/30.
Balla T. Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev. 2013;93(3):1019–137. Epub 2013/08/01.
Dechamps S, Shastri S, Wengelnik K, Vial HJ. Glycerophospholipid acquisition in Plasmodium – a puzzling assembly of biosynthetic pathways. Int J Parasitol. 2010;40(12):1347–65. Epub 2010/07/06.
Ginsburg H. Progress in in silico functional genomics: the malaria metabolic pathways database. Trends Parasitol. 2006;22(6):238–40. Epub 2006/05/19.
Kirk K. Membrane transport in the malaria-infected erythrocyte. Physiol Rev. 2001;81(2):495–537.
Lykidis A. Comparative genomics and evolution of eukaryotic phospholipid biosynthesis. Prog Lipid Res. 2007;46(3–4):171–99. Epub 2007/05/22.
Matsumoto K. Phosphatidylserine synthase from bacteria. Biochim Biophys Acta. 1997;1348(1–2):214–27. Epub 1997/11/25.
Ramakrishnan S, Serricchio M, Striepen B, Butikofer P. Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans. Prog Lipid Res. 2013;52(4):488–512. Epub 2013/07/06.
Schuiki I, Daum G. Phosphatidylserine decarboxylases, key enzymes of lipid metabolism. IUBMB Life. 2009;61(2):151–62. Epub 2009/01/24.
van Meer G, Voelker DR, Feigenson GW. Membrane lipids: where they are and how they behave. Nat Rev Mol Cell Biol. 2008;9(2):112–24. Epub 2008/01/25.
Vial HJ, Ancelin ML. Malarial lipids. An overview. Subcell Biochem. 1992;18:259–306.
Vial H, Ancelin M. Malarial lipids. In: Sherman I, editor. Malaria: parasite biology, biogenesis, protection. Washington, DC: ASM Press; 1998. p. 159–75.
Vial HJ, Penarete D, Wein S, Caldarelli S, Fraisse L, Peyrottes S. Lipids as drug targets for malaria therapy. In: Becker K, editor. Apicomplexan parasites: molecular approaches toward targeted drug development. Weinheim: Wiley-VCH; 2011. p. 544.
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Vial, H.J., Wengelnik, K. (2014). Phospholipid Metabolism. In: Hommel, M., Kremsner, P. (eds) Encyclopedia of Malaria. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8757-9_20-1
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