Definition
Enzyme-linked immunosorbent assay is a powerful diagnostic tool which, however, has only limited application in malaria diagnostics and research but may be the answer to a number of upcoming questions. This entry discusses potential applications and limitations of antigen and antibody detection by ELISA as a malaria diagnostic platform.
Introduction
In the history of the analysis of biomolecules, immunoassays together with various chromatographic and more recently molecular techniques have probably been the most commonly used technologies. Immunoassays are well suited for qualitative and quantitative assays of a single, well-defined molecular group. As compared to most other available methods, immunoassays can be developed that use less complex equipment and can be used in a wider range of testing environments.
Immunoassays take advantage of a natural phenomenon in order to quantify...
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Noedl, H. (2014). Malaria Diagnostic Platform, ELISA. In: Hommel, M., Kremsner, P. (eds) Encyclopedia of Malaria. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8757-9_107-1
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DOI: https://doi.org/10.1007/978-1-4614-8757-9_107-1
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