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Human Milk and the Premature Infant: Focus on Use of Pasteurized Donor Human Milk in the NICU

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Diet and Nutrition in Critical Care

Abstract

Human milk is the ideal source of nutrition for the healthy term infant and has significant advantages for the premature and/or critically ill infant. The advantages of unpasteurized mother’s own milk over pasteurized human donor milk include higher content of protein, fat, some minerals and vitamins, and several bioactive molecules. These advantages translate to better growth and fewer episodes of necrotizing enterocolitis among premature infants. Pasteurized donor human milk is the preferred nutrition for premature infants when the supply of mother’s own milk is limited. The following are likely to improve outcomes of premature and critically ill infants: increased use of mother’s own milk, increased availability of pasteurized donor human milk, and improved techniques for eliminating potential milk pathogens without decreasing the nutritional and bio-protective capacity of human milk.

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Abbreviations

CMV:

Cytomegalovirus

CRP:

C-reactive protein

DNA:

Deoxyribonucleic acid

HDL:

High-density lipoprotein

HIV:

Human immunodeficiency virus

HTLV:

Human T-cell lymphotropic virus

HTST:

High-temperature short-time

Ig:

Immunoglobulin

IL:

Interleukin

LDL:

Low-density lipoprotein

NEC:

Necrotizing enterocolitis

PDHM:

Pasteurized donor human milk

VLBW:

Very low birth weight

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Authors and Affiliations

  1. Department of Pediatrics, University of California Davis, 2516 Stockton Boulevard, Sacramento, CA, 95817, USA

    Mark A. Underwood & Jennifer A. Scoble

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  1. Mark A. Underwood
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  2. Jennifer A. Scoble
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Correspondence to Mark A. Underwood .

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  1. Department of Nutrition, King's College London, London, United Kingdom

    Rajkumar Rajendram

  2. School of Medicine, King's College London, London, United Kingdom

    Victor R. Preedy

  3. Department of Biomedical Sciences, University of Westminster, London, United Kingdom

    Vinood B. Patel

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Underwood, M.A., Scoble, J.A. (2014). Human Milk and the Premature Infant: Focus on Use of Pasteurized Donor Human Milk in the NICU. In: Rajendram, R., Preedy, V., Patel, V. (eds) Diet and Nutrition in Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8503-2_73-1

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