Encyclopedia of Database Systems

2018 Edition
| Editors: Ling Liu, M. Tamer Özsu

Implications of Genomics for Clinical Informatics

  • Mollie Ullman-CullereEmail author
  • Eugene Clark
  • Samuel Aronson
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-8265-9_194


Bioinformatics; Biomedical informatics; Clinical genetics; Clinical genomics; Medical genetics


Integration of genetic test results, generated in the clinical laboratory, into the electronic medical record, in a fully structured format enabling enhanced security, contextual views, clinical decision support, pharmacovigilance, disease management, outcomes and quality assessment.

Historical Background

Clinical genetics got its start in 1948 with the founding of the American Society of Human Genetics, which formalized a scientific approach to the study of human genetics [11]. Traditionally clinical genetics requires practitioners to function as data integrators. Like traditional healthcare, tests are ordered and results returned as interpretive reports delivered in paper form. Understanding the composite picture of the phenotype and genotypeof the patient requires transcribing key signs, symptoms, test values and their clinical interpretation into yet another...

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Recommended Reading

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Mollie Ullman-Cullere
    • 1
    Email author
  • Eugene Clark
    • 1
  • Samuel Aronson
    • 1
  1. 1.Harvard Medical School – Partners Healthcare Center for Genetics and GenomicsBostonUSA

Section editors and affiliations

  • Vipul Kashyap
    • 1
  1. 1.Director, Clinical ProgramsCIGNA HealthcareBloomfieldUSA