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l-Alanyl-l-glutamine Dipeptide-Supplemented Total Parenteral Nutrition

  • José Luis Flordelís Lasierra
  • Teodoro Grau Carmona
Reference work entry

Abstract

Glutamine is the most abundant free amino acid in the human body. It plays an important role in cellular metabolism and proliferation, as well as in immune regulation. It has been considered as “conditionally essential” in critical illnesses. The benefits behind using parenteral nutrition supplemented with glutamine on critically ill patients have received extensive support for many years from in vitro studies, animal models, and human studies. All of these have been further reinforced through systematic reviewing and meta-analysis. However, results from recent studies indicate that its prescription is controversial, it could be non-beneficial, and it may even be harmful if the patient type, timing, and dosage are not carefully selected.

Keywords

Parenteral Nutrition Enteral Nutrition Multiple Organ Dysfunction Syndrome Glutamine Supplementation Burnt Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations

Gln

Glutamine

ICU

Intensive care unit

MODS

Multiple organ dysfunction syndrome

PN

Parenteral nutrition

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • José Luis Flordelís Lasierra
    • 1
  • Teodoro Grau Carmona
    • 2
  1. 1.Intensive Care UnitHospital Sur de AlcorconAlcorcon, MadridSpain
  2. 2.Department of Intensive CareHospital Universitario Doce de OctubreMadridSpain

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