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Stem Cells Therapy for Hip Cartilage Lesions: General Concepts and Basic Science

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Hip Arthroscopy and Hip Joint Preservation Surgery

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Abstract

Hip cartilage lesions represent a diagnostic challenge and can be an elusive source of pain. Treatment may present difficulties due to localization and spherical form of the joint and is most commonly limited to excision, debridement, thermal chondroplasty, and microfractures. This chapter will focus on new technologies to enhance the standard techniques. These new technologies are based on stem cell therapies: as intra-articular injections of expanded mesenchymal stem cells, mononuclear concentrate in a platelet-rich plasma matrix, and expanded mesenchymal stem cells seeded in a collagen membrane. This review will discuss the bases, techniques, and preliminary results obtained with the use of stem cells for the treatment of hip cartilage lesions.

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Authors and Affiliations

  1. Orthopedics Department, Clínica Las Condes, Santiago, Chile

    Dr. Rodrigo Mardones M.D. (Head of Tissue Engineering Laboratory) & Dr. Catalina Larrain M.D.

Authors
  1. Dr. Rodrigo Mardones M.D.
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  2. Dr. Catalina Larrain M.D.
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Corresponding author

Correspondence to Rodrigo Mardones M.D. .

Editor information

Editors and Affiliations

  1. Dept. of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois, USA

    Shane Nho

  2. Dept. Orthopaedics, Hip Service, Schulthess Clinic, Zurich, Switzerland

    Michael Leunig

  3. Caspary Building, Ground Floor, Center for Hip Pain and Preservation, New York, New York, USA

    Bryan Kelly

  4. Department of Orthopaedics, University of Michigan Domino's Farms Lobby A, Ann Arbor, Michigan, USA

    Asheesh Bedi

  5. Twin Cities Orthopedics - Edina, Edina, Minnesota, USA

    Christopher Larson

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© 2014 Springer Science+Business Media New York

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Mardones, R., Larrain, C. (2014). Stem Cells Therapy for Hip Cartilage Lesions: General Concepts and Basic Science. In: Nho, S., Leunig, M., Kelly, B., Bedi, A., Larson, C. (eds) Hip Arthroscopy and Hip Joint Preservation Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7321-3_100-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7321-3_100-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7321-3

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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