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Globus Pallidus Cellular Models

Encyclopedia of Computational Neuroscience

Definition

The globus pallidus is a part of the basal ganglia in the vertebrate brain. Cellular models of the globus pallidus are computer representations of the specific dynamics of globus pallidus neurons.

Detailed Description

Goals of Globus Pallidus Cellular Models

Detailed cellular models of globus pallidus (GP) neurons are typically constructed to better understand how they integrate synaptic input and how their intrinsic properties contribute to the input–output function of the GP. The exploration of GP function in larger network models is typically carried out using less detailed cell models. The level of complexity and biological realism best used for a GP neuron model depends on the questions one wants to address (Herz et al. 2006) and ranges from simple integrate and fire models to complex full-morphological reconstructions with a full complement of ion channel types found in these neurons.

Models That Capture the Detailed Dynamic Properties of Globus Pallidus Neurons

The GP...

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Author information

Authors and Affiliations

  1. Department of Biology, Emory University, Atlanta, GA, USA

    Dieter Jaeger

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  1. Dieter Jaeger
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Correspondence to Dieter Jaeger .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Jaeger, D. (2014). Globus Pallidus Cellular Models. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_87-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_87-1

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  • Online ISBN: 978-1-4614-7320-6

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Chapter history

  1. Latest

    Basal Ganglia: Globus Pallidus Cellular Models
    Published:
    13 October 2019

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_87-2

  2. Original

    Globus Pallidus Cellular Models
    Published:
    12 February 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_87-1

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