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Sleep, Neural Population Models of

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Encyclopedia of Computational Neuroscience

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Definition

A neural population model of sleep is a mathematical model of neural populations that regulate the timing and expression of sleep/wake patterns. Specific circuits and nuclei have been identified in the mammalian brainstem and hypothalamus that play a key role in modulating the brain’s overall arousal state with a circadian (daily) rhythm. These neural populations have been the focus of most sleep modeling.

Detailed Description

Sleep is an arousal state characterized by physical inactivity, reduced sensitivity to environmental stimuli, and a range of characteristic physiological changes, including changes to the EEG associated with rapid eye movement (REM) and non-REM (NREM) sleep in mammals. Sleep is regulated by a variety of physiological and biochemical processes (Krueger et al. 2008; Saper et al. 2010), including specific neural populations in the brainstem and hypothalamus. Various mathematical models have now been developed, providing a conduit between the underlying...

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Authors and Affiliations

  1. Division of Sleep Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Dr. Andrew J. K. Phillips

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  1. Dr. Andrew J. K. Phillips
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Correspondence to Andrew J. K. Phillips .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Phillips, A.J.K. (2013). Sleep, Neural Population Models of. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_76-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_76-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7320-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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