Conductance-Based Models of Nonlinear Dynamics in Vertebrate Motoneurons
The term “conductance-based models of nonlinear dynamics in vertebrate motoneurons” refers to conductance-based motoneuron models that capture the complex nonlinear membrane properties (e.g., bistability) of vertebrate motoneurons observed both in vivo and in vitro under certain conditions. Numerous conductance-based motoneuron models with widely varying morphological complexities and different ionic current composition exist that reproduce the experimentally observed nonlinear membrane properties. This article focuses on models that assume minimally required morphological complexity (e.g., two compartments) and ionic conductances. The resulting reduced set of equations and parameters describing such models have enabled detailed analyses of model behavior using geometric dynamical systems methods to provide insight into the basis of nonlinear membrane properties in vertebrate motoneurons.