Definition
Bladder and bowel dysfunctions are frequently caused by neurological disease or injury such as spinal cord injury (SCI). With an annual incidence of 15–40 cases per million worldwide (Sekhon and Fehlings 2001), SCI results in neurogenic bladder or bowel dysfunction in a substantial percentage of cases (Levi et al. 1995). Surveys of quality-of-life measures in those with SCI show that the participants’ highest priorities were restoration of bladder/bowel function, restoration of sexual function, restoration of sensation, and elimination of chronic pain (Anderson 2004). In an earlier study, subjects with SCI indicated that bowel and bladder dysfunctions have a significant effect on their lives, ranking neurogenic bladder and bowel dysfunction as one of their major life-limiting problems (Hanson and Franklin 1976). Electrical stimulation...
References
Anderson KD (2004) Targeting recovery: priorities of the spinal cord-injured population. J Neurotrauma 21(10):1371–1383
Beckel JM, Holstege G (2011a) Neuroanatomy of the lower urinary tract. In: Andersson KE, Michel MC (eds) Urinary tract. Springer, Berlin, pp 99–116
Beckel JM, Holstege G (2011b) Neurophysiology of the lower urinary tract. In: Andersson KE, Michel MC (eds) Urinary tract. Springer, Berlin, pp 149–169
Benarroch EE (2010) Neural control of the bladder. Neurology 75(20):1839–1846
Benevento BT, Sipski ML (2002) Neurogenic bladder, neurogenic bowel, and sexual dysfunction in people with spinal cord injury. Phys Ther 82(6):601–612
Boggs JW, Wenzel BJ, Gustafson KJ, Grill WM (2006) Frequency-dependent selection of reflexes by pudendal afferents in the cat. J Physiol 577(1):115–126
Bradley WE, Chou SN, French LA (1963) Further experience with the radio transmitter receiver unit for the neurogenic bladders. J Neurosurg 20(11):953–960
Brindley G, Polkey C, Rushton DN (1982) Sacral anterior root stimulators for bladder control in paraplegia. Spinal Cord 20(6):365–381
Burns AS, Rivas DA, Ditunno JF (2001) The management of neurogenic bladder and sexual dysfunction after spinal cord injury. Spine (Phila Pa 1976) 26(24 Suppl):S129–S136
Chartier-Kastler EJ, Denys P, Chancellor MB, Haertig A, Bussel B, Richard F (2001) Urodynamic monitoring during percutaneous sacral nerve neurostimulation in patients with neurogenic detrusor hyperreflexia. Neurourol Urodyn 20(1):61–71
De Ridder D, Ost D, Bruyninckx F (2007) The presence of fowler’s syndrome predicts successful long-term outcome of sacral nerve stimulation in women with urinary retention. Eur Urol 51(1):229–234
Fowler CJ, Griffiths D, de Groat WC (2008) The neural control of micturition. Nat Rev Neurosci 9(6):453–466
Gaunt RA, Prochazka A (2006) Control of urinary bladder function with devices: successes and failures. Prog Brain Res 152:163–194
Glickman S, Kamm MA (1996) Bowel dysfunction in spinal-cord-injury patients. Lancet 347(9016):1651–1653
Gustafson KJ, Creasey GH, Grill WM (2004) A urethral afferent mediated excitatory bladder reflex exists in humans. Neurosci Lett 360(1–2):9–12
Hald T, Meier W, Khalili A, Agrawal G, Benton JG, Kantrowitz A (1967) Clinical experience with a radio-linked bladder stimulator. J Urol 97(1):73–78
Hanson RW, Franklin MR (1976) Sexual loss in relation to other functional losses for spinal cord injured males. Arch Phys Med Rehabil 57(6):291–293
Holmquist B, Olin T (1968) Electromicturition in male dogs at pelvic nerve stimulation: an urethrocystographic study. Scand J Urol Nephrol 2(2):115–127
Ishigooka M, Suzuki Y, Hashimoto T, Sasagawa I, Nakada T, Handa Y (1998) A new technique for sacral nerve stimulation: a percutaneous method for urinary incontinence caused by spinal cord injury. Br J Urol 81(2):315–318
Kinder MV, Bastiaanssen EHC, Janknegt RA, Marani E (1995) Neuronal circuitry of the lower urinary tract; central and peripheral neuronal control of the micturition cycle. Anat Embryol 192(3):195–209
Kirkham A, Shah N, Knight SL, Shah PJ, Craggs MD (2001) The acute effects of continuous and conditional neuromodulation on the bladder in spinal cord injury. Spinal Cord 39(8):420–428
Levi R, Hultling C, Nash MS, Seiger A (1995) The Stockholm spinal cord injury study: 1. Medical problems in a regional SCI population. Paraplegia 33(6):308–315
Nashold BS, Friedman H, Grimes J (1981) Electrical stimulation of the conus medullaris to control the bladder in the paraplegic patient. Appl Neurophysiol 44(4):225–232
Peng CW, Chen JJ, Cheng CL, Grill WM (2008) Role of pudendal afferents in voiding efficiency in the rat. Am J Physiol Regul Integr Comp Physiol 294(2):R660–R672
Previnaire JG, Soler JM, Perrigot M (1998) Is there a place for pudendal nerve maximal electrical stimulation for the treatment of detrusor hyperreflexia in spinal cord injury patients? Spinal Cord 36(2):100–103
Sekhon LH, Fehlings MG (2001) Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine (Phila Pa 1976) 26(24 Suppl):S2–S12
Shafik A, Shafik AA, El-Sibai O, Ahmed I (2003) Role of positive urethrovesical feedback in vesical evacuation. The concept of a second micturition reflex: the urethrovesical reflex. World J Urol 21(3):167–170
Stenberg CC, Burnette HW, Bunts RC (1967) Electrical stimulation of human neurogenic bladders: experience with 4 patients. J Urol 97(1):79–84
Stiens SA, Bergman SB, Goetz LL (1997) Neurogenic bowel dysfunction after spinal cord injury: clinical evaluation and rehabilitative management. Arch Phys Med Rehabil 78(3 Suppl):S86–S102
Tai C, Wang J, Wang X, de Groat WC, Roppolo JR (2007) Bladder inhibition or voiding induced by pudendal nerve stimulation in chronic spinal cord injured cats. Neurourol Urodyn 26(4):570–577
Vallès M, RodrÃguez A, Borau A, Mearin F (2009) Effect of sacral anterior root stimulator on bowel dysfunction in patients with spinal cord injury. Dis Colon Rectum 52(5):986–992
Vodusek DB, Light JK, Libby JM (1986) Detrusor inhibition induced by stimulation of pudendal nerve afferents. Neurourol Urodyn 5(4):381–389
Yoo P, Klein S, Grafstein NH, Horvath EE, Amundsen CL, Webster GD, Grill WM (2007) Pudendal nerve stimulation evokes reflex bladder contractions in persons with chronic spinal cord injury. Neurourol Urodyn 26(7):1020–1023
Further Reading
Furlan JC, Urbach DR, Fehlings MG (2007) Optimal treatment for severe neurogenic bowel dysfunction after chronic spinal cord injury: a decision analysis. Br J Surg 94(9):1139–1150
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media New York
About this entry
Cite this entry
McGee, M., Grill, W.M. (2013). Methodologies for the Restoration of Bladder and Bowel Functions. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_589-5
Download citation
DOI: https://doi.org/10.1007/978-1-4614-7320-6_589-5
Received:
Accepted:
Published:
Publisher Name: Springer, New York, NY
Online ISBN: 978-1-4614-7320-6
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences