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Encyclopedia of Computational Neuroscience pp 1–13Cite as

Local Field Potential and Movement Disorders

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Definition

Local field potentials (LFPs) represent the sum of low-frequency electrical activities in the extracellular medium close to a recording electrode. They predominately reflect field changes related to the flow of electrical current at synapses in the vicinity of the electrode, although other tissue components (neuronal spiking, glia potentials) may also contribute. The amplitude of LFPs is affected by the synchrony of dendritic potentials and by the geometry of dendritic arbors. Most of the electrical events that contribute to LFP signal occur within 200–400 μm of the tip of the electrode (Katzner et al. 2009; Xing et al. 2009).

LFPs can be recorded with microelectrodes, usually referenced against an electrode outside of the brain, or with macroelectrodes, usually as differential recordings between two poles of the same electrode. Because most of the spectral power of LFPs is found at relatively low frequencies (<300 Hz), LFP signals are often low-pass filtered (with a filter...

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Acknowledgment

This review entry was supported by grants from the National Institute of Health and National Institute of Neurological Disorders and Stroke R01-NS054976 and P50-NS071669 as well as an infrastructure grant from the NIH to the Yerkes Center (P51-RR165, now P51-OD11132).

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Authors and Affiliations

  1. Yerkes National Primate Research Center, Emory University, 954 Gatewood Road NE, Atlanta, GA, 30329, USA

    Annaelle Devergnas Ph.D. & Thomas Wichmann

  2. Department of Neurology, Emory University, Atlanta, GA, 30322, USA

    Thomas Wichmann

  3. Udall Center of Excellence in Parkinson’s Disease Research, Emory University, Atlanta, GA, 30329, USA

    Annaelle Devergnas Ph.D. & Thomas Wichmann

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  1. Annaelle Devergnas Ph.D.
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Correspondence to Annaelle Devergnas Ph.D. .

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Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Devergnas, A., Wichmann, T. (2014). Local Field Potential and Movement Disorders. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_551-1

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