Encyclopedia of Computational Neuroscience

Living Edition
| Editors: Dieter Jaeger, Ranu Jung

Short-Term Synaptic Plasticity in Central Pattern Generators

  • Diana MartinezEmail author
  • Victor Matveev
  • Farzan Nadim
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-7320-6_467-1



Short-term synaptic plasticity (STP) is a transient (milliseconds to minutes) activity-dependent change in the amplitude of the postsynaptic current in response to presynaptic activity. Central pattern generators (CPGs) are neural networks in the central nervous system capable of producing coordinated rhythmic output without rhythmic input from sensory organs or from higher control centers.

Detailed Description

Short-term synaptic plasticity (STP) is a transient (milliseconds to minutes) activity-dependent change in the amplitude (strength) of the postsynaptic current in response to presynaptic activity. It has clear implications for neural signaling and has been studied for several decades. Much of the modeling work has focused on the events in the presynaptic terminal and primarily on the role of Ca2+ in synaptic release of neurotransmitters (Zucker & Regehr 2002; Fioravante and Regehr 2011...


Central Pattern Generator Synaptic Depression Gastric Mill Pacemaker Neuron Readily Releasable Pool 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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This work was supported in part by NIH grant MH060605.


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© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Federated Department of Biological SciencesRutgers University, New Jersey Institute of TechnologyNewarkUSA
  2. 2.Department of Mathematical SciencesNew Jersey Institute of TechnologyNewarkUSA