Short-Term Synaptic Plasticity in Central Pattern Generators
Short-term synaptic plasticity (STP) is a transient (milliseconds to minutes) activity-dependent change in the amplitude of the postsynaptic current in response to presynaptic activity. Central pattern generators (CPGs) are neural networks in the central nervous system capable of producing coordinated rhythmic output without rhythmic input from sensory organs or from higher control centers.
Short-term synaptic plasticity (STP) is a transient (milliseconds to minutes) activity-dependent change in the amplitude (strength) of the postsynaptic current in response to presynaptic activity. It has clear implications for neural signaling and has been studied for several decades. Much of the modeling work has focused on the events in the presynaptic terminal and primarily on the role of Ca2+ in synaptic release of neurotransmitters (Zucker & Regehr 2002; Fioravante and Regehr 2011...
KeywordsCentral Pattern Generator Synaptic Depression Gastric Mill Pacemaker Neuron Readily Releasable Pool
This work was supported in part by NIH grant MH060605.
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