Background
Peripheral nerve trunks are composed of many individual nerve fibers (axons) which are segregated into several fascicles. The axons grouped in each fascicle tend to share a common peripheral endpoint, making them anatomically, if not functionally, distinct from those in other fascicles. This suggests that it may be feasible to identify the fascicles from which activity recorded by nerve cuff electrodes originates. For example, given several fascicles terminating separately in extensor and flexor muscle groups, this localization and subsequent separation of signals travelling to these groups could allow the control of prosthetics in people with amputated limbs.
Techniques
Techniques for source localization and separation in peripheral nerves are similar to those in other areas of biomedical signal localization and separation, such as EEG/MEG and ultrasound. These techniques are often referred to as beamforming (or spatial filtering) from ultrasound theory where transmit...
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Wodlinger, B. (2014). Peripheral Nerve Signal Processing, Source Localization. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_217-1
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DOI: https://doi.org/10.1007/978-1-4614-7320-6_217-1
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