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Encyclopedia of Computational Neuroscience pp 1–4Cite as

Peripheral Nerve Interface, Regenerative

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Definition

Regenerative peripheral interfaces (RPIs) are implantable devices that rely on the spontaneous regenerative capability of the injured peripheral nervous system to establish a bidirectional flow of information between the transected nerves in amputees and smart robotic prosthetics. RPIs are designed to provide intuitive movement and natural feel to advanced prosthetics for amputees and are characterized by the placement of multielectrode arrays (MEAs) in the regenerative path of their transected peripheral nerves. The MEAs detect motor commands from the brain as extracellular action potentials (AP) in the microvolt range traveling down their amputated nerves and use them to control the robotic prosthetic limb. In addition, RPIs can translate information from sensors populating the robotic limb to the user, by electrically stimulating axons in the nerve that elongate from neurons in the dorsal root ganglia.

Detailed Description

Regenerative Peripheral Interfaces (RPIs)

RPIs...

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Author information

Authors and Affiliations

  1. Department of Bioengineering, The University of Texas at Dallas, Richardson, TX, USA

    Dr. Mario Romero-Ortega

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  1. Dr. Mario Romero-Ortega
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Correspondence to Mario Romero-Ortega .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Romero-Ortega, M. (2014). Peripheral Nerve Interface, Regenerative. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_212-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_212-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7320-6

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