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Peripheral Nerve Interface Applications: Neuropathic Pain

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Encyclopedia of Computational Neuroscience

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Synonyms

Nerve pain; Neuralgia; Neurodynia

Definition

Neuropathic pain (NP) is a direct consequence of lesions or disease affecting the central or peripheral somatosensory system. Peripheral nerve interfaces are systems for delivery of therapeutic modalities directly to the peripheral nervous system, such as the management of NP.

Detailed Description

Pain is a subjective feeling of physical suffering and discomfort from the sensory modality of nociception (pain perception) by activation of terminal receptors. A direct activation of pain pathways can also result in the perception of pain without extrinsic activation of end receptors. Such “neuropathic pain” may be caused by disease or injury. The International Association for the Study of Pain (IASP) defined NP as “pain caused by a lesion or disease of the somatosensory system” (IASP 2011; Jensen et al. 2011).

Patients with NP may have reduced sensation to touch and temperature in affected areas (negative signs and symptoms). They may...

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Further Reading

  • Devor M (2012) Peripheral neuropathic pain. In: Schmidt RF, Gebhart GF (eds) Encyclopedia of pain. Springer. http://link.springer.com/book/10.1007%2F978-3-642-28753-4

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Author information

Authors and Affiliations

  1. Neural Engineering Center, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA

    Narendra Bhadra

Authors
  1. Narendra Bhadra
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Corresponding author

Correspondence to Narendra Bhadra .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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© 2014 Springer Science+Business Media New York

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Bhadra, N. (2014). Peripheral Nerve Interface Applications: Neuropathic Pain. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_203-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_203-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7320-6

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