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Definition
In response to acoustic inputs (sounds), neural activity generates extracellular voltages throughout the auditory pathway. Sound-evoked extracellular voltages in the auditory brainstem – termed the neurophonic – exhibit distinctive temporal and spatial patterns. Computational modeling demonstrates how neural activity in an auditory brainstem region known as the medial superior olive (MSO) can produce these extracellular voltages.
Detailed Description
Extracellular Voltage Recordings in the Auditory Brainstem
An important center of auditory processing in the auditory pathway is the medial superior olive (MSO). In this nucleus, neurons receive inputs that originate from both ears. Spiking activity of MSO neurons is sensitive to the relative timing of synaptic inputs, which allows these neurons to convey information about interaural time differences, an important cue for sound source location (Grothe et al. 2010).
In addition to evoking...
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References
Biedenbach MA, Freeman WJ (1964) Click-evoked potential map from the superior olivary nucleus. Am J Physiol-Legacy Content 206(6):1408–1414
Boudreau JC (1965) Neural volleying: upper frequency limits detectable in the auditory system. Nature 208(5016):1237–1238
Einevoll GT, Kayser C, Logothetis NK, Panzeri S (2013) Modelling and analysis of local field potentials for studying the function of cortical circuits. Nat Rev Neurosci 14(11):770–785
Franken TP, Roberts MT, Wei L, Golding NL, Joris PX (2015) In vivo coincidence detection in mammalian sound localization generates phase delays. Nat Neurosci 18(3):444–452
Galambos R, Schwartzkopff J, Rupert A (1959) Microelectrode study of superior olivary nuclei. Am J Physiol-Legacy Content 197(3):527–536
Goldwyn JH, Rinzel J (2016) Neuronal coupling by endogenous electric fields: cable theory and applications to coincidence detector neurons in the auditory brain stem. J Neurophysiol 115:2033–2051
Goldwyn JH, Mc Laughlin M, Verschooten E, Joris PX, Rinzel J (2014) A model of the medial superior olive explains spatiotemporal features of local field potentials. J Neurosci 34(35):11705–11722
Goldwyn JH, Mc Laughlin M, Verschooten E, Joris PX, Rinzel J (2017) Signatures of somatic inhibition and dendritic excitation in auditory brainstem field potentials. J Neurosci 37(43):10451–10467
Grothe B, Pecka M, Mcalpine D (2010) Mechanisms of sound localization in mammals. Physiol Rev 90(3):983–1012
Mc Laughlin M, Verschooten E, Joris PX (2010) Oscillatory dipoles as a source of phase shifts in field potentials in the mammalian auditory brainstem. J Neurosci 30(40):13472–13487
Rall W, Shepherd GM (1968) Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb. J Neurophysiol 31(6):884–915
Rautenberg PL, Grothe B, Felmy F (2009) Quantification of the threedimensional morphology of coincidence detector neurons in the medial superior olive of gerbils during late postnatal development. J Comp Neurol 517(3):385–396
Tsuchitani C, Boudreau JC (1964) Wave activity in the superior olivary complex of the cat. J Neurophysiol 27:814–827
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Goldwyn, J.H., Verschooten, E., Mc Laughlin, M. (2019). Extracellular Voltage Recordings in the Medial Superior Olive, Modeling of. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_100688-1
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DOI: https://doi.org/10.1007/978-1-4614-7320-6_100688-1
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