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Encyclopedia of Computational Neuroscience pp 1–8Cite as

Large-Scale Models of the Olfactory Bulb

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Synonyms

Deep short-axon cells; Feedforward inhibition; Glomerular layer; Granule cells; Large-scale models of the OB; Lateral inhibition; Mitral cells; Odor learning; Odor processing; Periglomerular cells; Tufted cells

Definition

The olfactory bulb (OB) is a small, self-contained system that is pivotally involved in generating the sense of the smell. Large-scale models of the olfactory bulb reconstruct extensive portions of it, including the main neuron populations (i.e., mitral, tufted, and granule cells), along with their connectivity and glomerular organization. Large-scale models of the OB therefore comprise of three components: (i) a model of odor inputs, (ii) cell models of the main neuron classes, and (iii) computational models of feedforward and/or feedback inhibition.

Detailed Description

Analyses of large portions of the olfactory bulb (OB) are the key to understand odor processing. In the OB, odor-specific spatiotemporal patterns characterize odor response (Abraham et al. 2004...

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Author information

Authors and Affiliations

  1. Department of Biology, Emory University, Atlanta, GA, USA

    Francesco Cavarretta

Authors
  1. Francesco Cavarretta
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Corresponding author

Correspondence to Francesco Cavarretta .

Editor information

Editors and Affiliations

  1. Atlanta, GA, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, FL, USA

    Ranu Jung

Section Editor information

  1. National Research Council, Institute of Biophysics, Palermo, Italy

    Michele Migliore

  2. Computational Physiology Lab, Department of Neurobiology and Behavior, Cornell University, Ithaca, NY, USA

    Christiane Linster

  3. Department of Biology, Emory University, Atlanta, GA, USA

    Francesco Cavarretta

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Cavarretta, F. (2021). Large-Scale Models of the Olfactory Bulb. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_100664-2

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_100664-2

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-7320-6

  • Online ISBN: 978-1-4614-7320-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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Chapter history

  1. Latest

    Large-Scale Models of the Olfactory Bulb
    Published:
    24 February 2021

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_100664-2

  2. Original

    Large-Scale Models of the Olfactory Bulb
    Published:
    12 November 2018

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_100664-1

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