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Congenital Melanocytic Naevi

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Melanoma

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Abstract

The term congenital melanocytic naevi (CMN) covers a broad spectrum of clinical presentations, ranging from the common occurrence of small single CMN, to the rare occurrence of extensive and very numerous CMN accompanied by extra-cutaneous abnormalities. The study of these diseases is relevant to the wider understanding of naevogenesis and melanoma development and provides potentially powerful insights due to the lack of influence of ultraviolet radiation on the prenatal genetic events. Recent improved understanding of the pathogenesis of CMN, and of the relatively rare progression to melanoma, is contributing to the management of individuals affected by these conditions. In this chapter, current knowledge in this field and the authors’ approach to management of this multifaceted disease will be reviewed.

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Authors and Affiliations

  1. Paediatric Dermatology Department, Great Ormond Street Hospital for Children, London, UK

    Veronica A. Kinsler

  2. Division of Pediatric Pathology, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA

    Miguel Reyes-Mugica

  3. Hauppauge Dermatology Section, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Ashfaq Marghoob

Authors
  1. Veronica A. Kinsler
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  2. Miguel Reyes-Mugica
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  3. Ashfaq Marghoob
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Corresponding author

Correspondence to Veronica A. Kinsler .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Harvard/MGH Cutaneous Biology Research Center, and Melanoma Program, MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    David E. Fisher

  2. Departments of Dermatology and Pathology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA

    Boris C. Bastian

Section Editor information

  1. Departments of Dermatology and Pathology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA

    Boris C. Bastian

  2. Auburndale, MA, USA

    Hensin Tsao

  3. Harvard-MIT Health Sciences and Technology, Cambridge, MA, USA

    Hensin Tsao

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Kinsler, V.A., Reyes-Mugica, M., Marghoob, A. (2019). Congenital Melanocytic Naevi. In: Fisher, D., Bastian, B. (eds) Melanoma. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7147-9_3

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  • DOI: https://doi.org/10.1007/978-1-4614-7147-9_3

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