Encyclopedia of Computational Neuroscience

2015 Edition
| Editors: Dieter Jaeger, Ranu Jung

Resistivity, Axial

  • John Bekkers
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6675-8_35

Synonyms

Definition

The axial resistivity, Ri, is a measure of the Ohmic resistance of the intracellular medium of a neuronal process (e.g., axon or dendrite). Ri is defined as the resistance of the medium contained within a fixed-radius cylinder of unit length and unit cross-sectional area, measured between the flat ends of the cylinder. The most commonly used units are Ω cm, in which case the dimensions of the cylinder are in cm. For neurons, Ri is typically on the order of 100 Ω cm.

Detailed Description

Explanation of the Units

R i is a specific property of the intracellular medium that should not depend on the dimensions of the cylinder across which it is measured. If the length of the unit cylinder is increased to length L cm, then the total resistance, R T, measured from one end of the cylinder to the other increases to R i L, because current needs to flow...
This is a preview of subscription content, log in to check access.

References

  1. Bekkers JM (2011) Changes in dendritic axial resistance alter synaptic integration in cerebellar Purkinje cells. Biophys J 100:1198–1206PubMedCentralPubMedGoogle Scholar
  2. Bloodgood BL, Sabatini BL (2005) Neuronal activity regulates diffusion across the neck of dendritic spines. Science 310:866–869PubMedGoogle Scholar
  3. Hodgkin AL, Keynes RD (1953) The mobility and diffusion coefficient of potassium in giant axons from Squid. J Physiol 119:513–528PubMedCentralPubMedGoogle Scholar
  4. Hodgkin AL, Rushton WAH (1946) The electrical constants of a crustacean nerve fibre. Proc R Soc B133:444–479Google Scholar
  5. Jack JJB, Noble D, Tsien RW (1983) Electrical current flow in excitable cells. Oxford University Press, OxfordGoogle Scholar
  6. Major G, Larkman AU, Jonas P, Sakmann B, Jack JJB (1994) Detailed passive cable models of whole-cell recorded CA3 pyramidal neurons in rat hippocampal slices. J Neurosci 14:4613–4638PubMedGoogle Scholar
  7. Roth A, Häusser M (2001) Compartmental models of rat cerebellar Purkinje cells based on simultaneous somatic and dendritic patch-clamp recordings. J Physiol 535:445–472PubMedCentralPubMedGoogle Scholar
  8. Stuart G, Spruston N (1998) Determinants of voltage attenuation in neocortical pyramidal neuron dendrites. J Neurosci 18:3501–3510PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Australian National UniversityCanberraAustralia