Skip to main content

Framingham Offspring Study

  • Living reference work entry
  • Latest version View entry history
  • First Online:
Book cover Encyclopedia of Behavioral Medicine
  • 20 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References and Further Reading

  • Ai, M., Otokozawa, S., Asztalos, B. F., White, C. C., Cupples, L. A., Nakajima, K., et al. (2011). Adiponectin: An independent risk factor for coronary heart disease in men in the Framingham Offspring Study. Atherosclerosis, 217(2), 543–548.

    Article  CAS  Google Scholar 

  • Andersson, C., Quiroz, R., Enserro, D., Larson, M. G., Hamburg, N. M., Vita, J. A., et al. (2016). Association of parental hypertension with arterial stiffness in nonhypertensive offspring: The Framingham Heart Study. Hypertension, 68(3), 584–589.

    Article  CAS  Google Scholar 

  • Aparicio, H. J., Petrea, R. E., Massaro, J. M., Manning, W. J., Oyama-Manabe, N., Beiser, A. S., et al. (2017). Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study. Atherosclerosis, 265, 305–311. https://doi.org/10.1016/j.atherosclerosis.2017.06.919.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Duncan, M. S., Vasan, R. S., & Xanthakis, V. (2019). Trajectories of blood lipid concentrations over the adult life course and risk of cardiovascular disease and all-cause mortality: Observations from the Framingham Study over 35 years. Journal of the American Heart Association, 8(11), e011433. https://doi.org/10.1161/jaha.118.011433.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Eaker, E. D., Sullivan, L. M., Kelly-Hayes, M., D’Agostino, R. B., Sr., & Benjamin, E. J. (2004). Anger and hostility predict the development of atrial fibrillation in men in the Framingham Offspring Study. Circulation, 109(10), 1267–1271.

    Article  Google Scholar 

  • Elias, M. F., Sullivan, L. M., Elias, P. K., D’Agostino, R. B., Sr., Wolf, P. A., Seshadri, S., et al. (2007). Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham Offspring. Hypertension, 49(3), 439–445.

    Article  CAS  Google Scholar 

  • Enserro, D. M., Vasan, R. S., & Xanthakis, V. (2018). Twenty-year trends in the American Heart Association Cardiovascular Health Score and impact on subclinical and clinical cardiovascular disease: The Framingham Offspring Study. Journal of the American Heart Association, 7(11), e008741. https://doi.org/10.1161/JAHA.118.008741.

    Article  PubMed  PubMed Central  Google Scholar 

  • Feinleib, M., Kannel, W. B., Garrison, R. J., McNamara, P. M., & Castelli, W. P. (1975). The Framingham Offspring Study. Design and preliminary data. Preventive Medicine, 4(4), 518–525.

    Article  CAS  Google Scholar 

  • Frankel, D. S., Meigs, J. B., Massaro, J. M., Wilson, P. W., O’Donnell, C. J., D’Agostino, R. B., et al. (2008). Von Willebrand factor, type 2 diabetes mellitus, and risk of cardiovascular disease: The Framingham Offspring Study. Circulation, 118(24), 2533–2539.

    Article  CAS  Google Scholar 

  • Gupta, A., Preis, S. R., Beiser, A., Devine, S., Hankee, L., Seshadri, S., et al. (2015). Mid-life cardiovascular risk impacts memory function: The Framingham Offspring Study. Alzheimer Disease and Associated Disorders, 29(2), 117–123.

    PubMed  PubMed Central  Google Scholar 

  • Khera, A. V., Won, H. H., Peloso, G. M., Lawson, K. S., Bartz, T. M., Deng, X., et al. (2016). Diagnostic yield and clinical utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia. Journal of the American College of Cardiology, 67(22), 2578–2589. https://doi.org/10.1016/j.jacc.2016.03.520.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li, W., Dorans, K. S., Wilker, E. H., Rice, M. B., Ljungman, P. L., Schwartz, J. D., et al. (2019). Short-term exposure to ambient air pollution and circulating biomarkers of endothelial cell activation: The Framingham Heart Study. Environmental Research, 171, 36–43. https://doi.org/10.1161/ATVBAHA.117.309799.

    Article  CAS  PubMed  Google Scholar 

  • Loucks, E. B., Abrahamowicz, M., Xiao, Y., & Lynch, J. W. (2011). Associations of education with 30 year life course blood pressure trajectories: Framingham Offspring Study. BMC Public Health, 11, 139.

    Article  Google Scholar 

  • McKeown, N. M., Meigs, J. B., Liu, S., Wilson, P. W., & Jacques, P. F. (2002). Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study. American Journal of Clinical Nutrition, 76(2), 390–398.

    Article  CAS  Google Scholar 

  • McKeown, N. M., Meigs, J. B., Liu, S., Saltzman, E., Wilson, P. W., & Jacques, P. F. (2004). Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort. Diabetes Care, 27(2), 538–546.

    Article  Google Scholar 

  • McManus, D. D., Rong, J., Huan, T., Lacey, S., Tanriverdi, K., Munson, P. J., et al. (2017). Messenger RNA and microRNA transcriptomic signatures of cardiometabolic risk factors. BMC Genomics, 18(1), 139. https://doi.org/10.1186/s12864-017-3533-9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • McManus, D. D., Trinquart, L., Benjamin, E. J., Manders, E. S., Fusco, K., Jung, L. S., et al. (2019). Design and preliminary findings from a new electronic cohort embedded in the Framingham Heart Study. Journal of Medical Internet Research, 21(3), e12143. https://doi.org/10.2196/12143.

    Article  PubMed  PubMed Central  Google Scholar 

  • Raghavan, S., Pachucki, M. C., Chang, Y., Porneala, B., Fox, C. S., Dupuis, J., et al. (2016). Incident type 2 diabetes risk is influenced by obesity and diabetes in social contacts: A social network analysis. Journal of General Internal Medicine, 31(10), 1127–1133. https://doi.org/10.1007/s11606-016-3723-1.

    Article  PubMed  PubMed Central  Google Scholar 

  • Romero, J. R., Vasan, R. S., Beiser, A. S., Polak, J. F., Benjamin, E. J., Wolf, P. A., et al. (2008). Association of carotid artery atherosclerosis with circulating biomarkers of extracellular matrix remodeling: The Framingham Offspring Study. Journal of Stroke and Cerebrovascular Diseases, 17(6), 412–417.

    Article  Google Scholar 

  • Smith, B. T., Lynch, J. W., Fox, C. S., Harper, S., Abrahamowicz, M., Almeida, N. D., et al. (2011). Life-course socioeconomic position and type 2 diabetes mellitus: The Framingham Offspring Study. American Journal of Epidemiology, 173(4), 438–447.

    Article  Google Scholar 

  • Tan, Z. S., Spartano, N. L., Beiser, A. S., DeCarli, C., Auerbach, S. H., Vasan, R. S., et al. (2016). Physical activity, brain volume, and dementia risk: The Framingham Study. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 72(6), 789–795. https://doi.org/10.1093/gerona/glw130.

    Article  CAS  PubMed Central  Google Scholar 

  • Wilson, P. W., Garrison, R. J., Castelli, W. P., Feinleib, M., McNamara, P. M., & Kannel, W. B. (1980). Prevalence of coronary heart disease in the Framingham Offspring Study: Role of lipoprotein cholesterols. The American Journal of Cardiology, 46(4), 649–654.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andrew J. Wawrzyniak .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Science+Business Media, LLC, part of Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Wawrzyniak, A.J. (2020). Framingham Offspring Study. In: Gellman, M. (eds) Encyclopedia of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6439-6_803-3

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-6439-6_803-3

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-6439-6

  • Online ISBN: 978-1-4614-6439-6

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Chapter history

  1. Latest

    Framingham Offspring Study
    Published:
    23 January 2020

    DOI: https://doi.org/10.1007/978-1-4614-6439-6_803-3

  2. Original

    Framingham Offspring Study
    Published:
    12 April 2017

    DOI: https://doi.org/10.1007/978-1-4614-6439-6_803-2