Encyclopedia of Behavioral Medicine

Living Edition
| Editors: Marc Gellman

Kuopio Ischemic Heart Disease Risk Factor Study

  • Kauhanen JussiEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6439-6_328-2



The Kuopio Ischemic Heart Disease Risk Factor Study (KIHD) is an extensive epidemiologic research project that was launched in the 1980s. Within 30 years, it has produced over 500 original peer-reviewed research papers in health-related international journals. The KIHD is a population-based longitudinal follow-up study, which initially involved nearly 3,000 middle-aged (42–60 years) men from the Kuopio region in Eastern Finland. Ten years later, women of the same age (N > 1,000) were recruited to the study. A major part of the original cohorts have been reexamined 4, 11, and 20 years after the baseline. Register linkages have been established with national covering registries, i.e., the National Death Registry of Finland, Hospital Discharge Registry, Cancer Registry, Kela prescription drug registry, and other disease-specific national health registries in Finland, to monitor annual...


Binge Drinking Hospital Discharge Registry Blood Pressure Reactivity Prescription Drug Registry Ongoing Prospective Study 
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References and Further Readings

  1. Emerging Risk Factors Collaboration. (2012). C-reactive protein, fibrinogen, and cardiovascular disease prediction. New England Journal of Medicine, 367(14), 1310–1320. doi:10.1056/NEJMoa1107477.CrossRefGoogle Scholar
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  4. Kauhanen, L., Lynch, J. W., Lakka, H. M., Kauhanen, J., & Smith, G. D. (2010). Association of diarrhoea, poor hygiene and poor social conditions in childhood with blood pressure in adulthood. Journal of Epidemiology and Community Health, 64, 394–399.CrossRefPubMedGoogle Scholar
  5. Kurl, S., Laaksonen, D. E., Jae, S. Y., Mäkikallio, T. H., Zaccardi, F., Kauhanen, J., Ronkainen, K., & Laukkanen, J. A. (2016). Metabolic syndrome and the risk of sudden cardiac death in middle-aged men. International Journal of Cardiology, 203, 792–797.CrossRefPubMedGoogle Scholar
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  7. Laukkanen, T., Khan, H., Zaccardi, F., & Laukkanen, J. A. (2015). Association between sauna bathing and fatal cardiovascular and all-cause mortality events. JAMA Internal Medicine, 175(4), 542–548.CrossRefPubMedGoogle Scholar
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  9. Salonen, J. T., Seppänen, K., Nyyssönen, K., Korpela, H., Kauhanen, J., Kantola, M., Tuomilehto, J., Esterbauer, H., Tatzber, F., & Salonen, R. (1995). Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men. Circulation, 91(3), 645–655.CrossRefPubMedGoogle Scholar
  10. Virtanen, J. K., Mursu, J., Virtanen, H. E., Fogelholm, M., Salonen, J. T., Koskinen, T. T., Voutilainen, S., Tuomainen, T. P. (2016). Associations of egg and cholesterol intakes with carotid intima-media thickness and risk of incident coronary artery disease according to apolipoprotein E phenotype in men: the Kuopio Ischemic Heart Disease Risk Factor Study. The American Journal of Clinical Nutrition, 103(3):895–901. doi: 10.3945/ajcn.115.122317. pii: ajcn122317.Google Scholar

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Institute of Public Health and Clinical NutritionUniversity of Eastern FinlandKuopioFinland