Kuopio Ischemic Heart Disease Risk Factor Study
The Kuopio Ischemic Heart Disease Risk Factor Study (KIHD) is an extensive epidemiologic research project that was launched in the 1980s. Within 30 years, it has produced over 500 original peer-reviewed research papers in health-related international journals. The KIHD is a population-based longitudinal follow-up study, which initially involved nearly 3,000 middle-aged (42–60 years) men from the Kuopio region in Eastern Finland. Ten years later, women of the same age (N > 1,000) were recruited to the study. A major part of the original cohorts have been reexamined 4, 11, and 20 years after the baseline. Register linkages have been established with national covering registries, i.e., the National Death Registry of Finland, Hospital Discharge Registry, Cancer Registry, Kela prescription drug registry, and other disease-specific national health registries in Finland, to monitor annual...
KeywordsBinge Drinking Hospital Discharge Registry Blood Pressure Reactivity Prescription Drug Registry Ongoing Prospective Study
References and Further Readings
- Salonen, J. T., Seppänen, K., Nyyssönen, K., Korpela, H., Kauhanen, J., Kantola, M., Tuomilehto, J., Esterbauer, H., Tatzber, F., & Salonen, R. (1995). Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men. Circulation, 91(3), 645–655.CrossRefPubMedGoogle Scholar
- Virtanen, J. K., Mursu, J., Virtanen, H. E., Fogelholm, M., Salonen, J. T., Koskinen, T. T., Voutilainen, S., Tuomainen, T. P. (2016). Associations of egg and cholesterol intakes with carotid intima-media thickness and risk of incident coronary artery disease according to apolipoprotein E phenotype in men: the Kuopio Ischemic Heart Disease Risk Factor Study. The American Journal of Clinical Nutrition, 103(3):895–901. doi: 10.3945/ajcn.115.122317. pii: ajcn122317.Google Scholar