Definition
A follow-up study, more commonly called a cohort study, has three basic components: exposure, time, and outcome. A group of individuals (the cohort) is assembled and then assessed at baseline on the exposure of interest (a risk or protective factor), other risk factors known to influence the outcome of interest (i.e., potential confounders), and the prevalence of the outcome of interest. Subjects who have the outcome (a disease) are excluded, and those remaining are followed over time to determine the development of the outcome. Incidence of the outcome is then compared in those with and without the exposure, controlling for extraneous confounders.
Description
Follow-up studies have various names derived from either study group (cohort studies), the timing of observation (follow-up, prospective or longitudinal studies), or the disease outcome (incidence studies). They begin with the assembly of a...
References and Further Reading
Gordis, L. (2009). Epidemiology (4th ed.). Philadelphia: Saunders Elsevier.
Hedeker, D. R., & Gibbons, R. D. (2006). Longitudinal data analysis. Hoboken: Wiley.
Little, R. J., & Rubin, D. B. (2019). Statistical analysis with missing data (3rd ed.). Hoboken: Wiley.
Szklo, M., & Nieto, F. J. (2014). Epidemiology: Beyond the basics. Sudbury: Jones & Bartlett Publishers.
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gotzsche, P. C., Vandenbroucke, J. P., & STROBE Initiative. (2008). The strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies. Journal of Clinical Epidemiology, 61(4), 344–349. https://doi.org/10.1016/j.jclinepi.2007.11.008.
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Powell, L.H., Lange-Maia, B., Janssen, I. (2020). Follow-Up Study. In: Gellman, M. (eds) Encyclopedia of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6439-6_314-2
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DOI: https://doi.org/10.1007/978-1-4614-6439-6_314-2
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