Encyclopedia of Behavioral Medicine

Living Edition
| Editors: Marc Gellman

Lupus: Psychosocial Impact

  • Yori GidronEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6439-6_1431-2


Lupus is a brief name of the formal medical term systemic lupus erythematosus (SLE). This is an autoimmune disease, affecting different organs in the body including the heart, lungs, skin, joints, and nervous system. It can be life threatening, though the advancement in medical treatment has made this outcome rare. Sadly, SLE mimics other illnesses in that its symptoms overlap with many other diseases; hence, patients may be misdiagnosed for long periods of time. It is prevalent mainly in women, between 15 and 35 years old. In SLE, the immune system produces antibodies against proteins in cell nuclei. Furthermore, various immune cells show excessive apoptosis, whose level correlates with disease activity. About 30 % have skin symptoms (e.g., red rashes); many patients have joint pain, particularly in the hands and wrist, muscle pain, and anemia. Finally, cardiac inflammation and atherosclerosis are common. Some of the symptoms such as weight gain and retinal damage also...

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References and Further Readings

  1. Beckerman, N. L., Auerbach, C., & Blanco, I. (2011). Psychosocial dimensions of SLE: Implications for the health care team. Journal of Multidisciplinary Healthcare, 4, 63–72.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Líndal, E., Thorlacius, S., Steinsson, K., & Stefánsson, J. G. (1995). Psychiatric disorders among subjects with systemic lupus erythematosus in an unselected population. Scandinavian Journal of Rheumatology, 24, 346–351.CrossRefPubMedGoogle Scholar
  3. Pawlak, C. R., Witte, T., Heiken, H., Hundt, M., Schubert, J., Wiese, B., et al. (2003). Flares in patients with systemic lupus erythematosus are associated with daily psychological stress. Psychotherapy and Psychosomatics, 72, 159–165.CrossRefPubMedGoogle Scholar
  4. Simard, J. F., & Costenbader, K. H. (2007). What can epidemiology tell us about systemic lupus erythematosus? International Journal of Clinical Practice, 61, 1170–1180.CrossRefPubMedGoogle Scholar
  5. Yorgun, H., Canpolat, U., Aytemir, K., Ateş, A. H., Kaya, E. B., Akdoğan, A., Sunman, H., Gökçay Canpolat, A., Çalgüneri, M., Kabakçi, G., Tokgözoğlu, L., & Oto, A. (2012). Evaluation of cardiac autonomic functions in patients with systemic lupus erythematosus. Lupus, 21, 373–379.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.SCALabLille 3 University and Siric OncollileLilleFrance